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significant results » significant reductions (Expand Search), significant reduction (Expand Search)
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19521
Table 2_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.docx
Published 2025“…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …”
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19522
Workflow of the study.
Published 2025“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”
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19523
Scaling analyses and morphometrics of <i>Ginkgo biloba</i> seeds
Published 2025“…When seeds were grouped by the ellipsoid index (EI = <i>V</i>/<i>V</i><sub>E</sub>), the scaling exponent of <i>V</i> vs. <i>M</i> decreased from values significantly greater than one to values less than one as EI increased. …”
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19524
Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease
Published 2025“…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”
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19525
Table 2_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx
Published 2025“…Bayesian Age-Period-Cohort (BAPC) modeling was used to predict the incidence rates of different sex and age groups in 2036.</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”
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19526
<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor
Published 2025“…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …”
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19527
DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx
Published 2024“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”
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19528
Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…Bone marrow-derived macrophages and neutrophils were isolated to evaluate GM-CSF’ s impact on chemotaxis, phagocytosis, and killing functions.</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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19529
Image 6_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg
Published 2024“…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …”
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19530
Image 1_Yacon root is a functional food beneficial for human health: a meta-analysis of clinical trials.pdf
Published 2025“…Twelve studies were included in the analysis. The pooled results showed that YR significantly reduced BMI [SMD = −0.81, 95%CI (−1.54, −0.08)], decreased stool pH [SMD = −1.12, 95%CI (−1.61, −0.62)], softened stools [SMD = 0.94, 95%CI (0.08, 1.80)], facilitated defecation [SMD = 4.03, 95% CI (0.54, 7.52)], improved fiber consumption patterns [SMD = 0.58, 95%CI (0.18, −0.99)]. …”
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19531
Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx
Published 2025“…The primary outcome was new functional morbidity, defined as at least a one-point increase in the pediatric overall performance category from baseline to hospital discharge.</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
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19532
Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc
Published 2025“…COS-PA application decreased leaf Na<sup>+</sup> content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca<sup>2+</sup> content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …”
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19533
Image 9_Isolation and identification of Alternaria alstroemeriae causing postharvest black rot in citrus and its control using curcumin-loaded nanoliposomes.jpeg
Published 2025“…Curcumin-loaded nanoliposomes also enhanced the activities of the enzymes PPO, APX, POD, PAL, GR and CAT of citrus, decreased the O<sub>2</sub><sup>−</sup> production rate. …”
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19534
Table 1_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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19535
Table 1_Angiotensin converting enzyme inhibitors and angiotensin receptor blockers impact on the gut microbiome: a systematic review.docx
Published 2025“…In the human study, ACEi/ARB use did not significantly alter microbial diversity, but decreased populations of facultative aerobic pathogens including Staphylococcus and Enterobacterales. …”
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19536
Table 4_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx
Published 2025“…Bayesian Age-Period-Cohort (BAPC) modeling was used to predict the incidence rates of different sex and age groups in 2036.</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”
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19537
Table 1_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.docx
Published 2024“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”
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19538
Data Sheet 1_Peripheral circular RNAs hsa_circ_0075436 and hsa_circ_0005729 as diagnostic and prognostic biomarkers in acute ischemic stroke: expression profiles and mechanistic in...
Published 2025“…Functional enrichment analysis and competing endogenous RNA (ceRNA) network construction were conducted to explore potential regulatory mechanisms.</p>Results<p>Two circRNAs, hsa_circ_0075436 and hsa_circ_0005729, significantly decreased in PBMCs of AIS patients. …”
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19539
Table 1_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.xlsx
Published 2025“…Propensity score matching (PSM) was used to validate the predictive value of baseline NK cell proportion for CAVEs.</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”
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19540
Table 5_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx
Published 2025“…Bayesian Age-Period-Cohort (BAPC) modeling was used to predict the incidence rates of different sex and age groups in 2036.</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”