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significant risk » significant role (Expand Search)
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18261
Table 12_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18262
Effect of soil and plant nutrients on starch yield of potato for processing under growers’ management in Hokkaido, Japan
Published 2025“…Our findings indicate that higher soil available N decreases starch yield. In general, the soil available N in the growers’ fields was high to excessive, and shoot N concentrations were positively related to soil available N. …”
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18263
Data Sheet 1_Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled...
Published 2025“…Furthermore, the score of AMS in the curcumin group were lower than those in the placebo group at T<sub>3</sub>, although with no significant difference. Gut microbiota analysis indicated that curcumin significantly increased the abundance of butyrate-producing bacteria Roseburia, Lachnospira, and Sellimonas while decreasing the abundance of Alistipes and Escherichia at high-altitude environments. …”
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18264
Table 1_An evaluation of the impact of abattoir processing on the levels of Campylobacter spp. and Enterobacteriaceae on broiler carcasses.docx
Published 2025“…Hot water immersion and ultrasound intervention substantially decreased Campylobacter levels by 0.85 log<sub>10</sub> and Enterobacteriaceae levels by 0.82 log<sub>10</sub>. …”
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18265
Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated...
Published 2024“…In co-cultures with NK cells and K562 target cells, we observed that Galectin-3-induced production of reactive oxygen species in neutrophils resulted in decreased NK cell viability and lowered anti-tumor responses.…”
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18266
Image 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18267
Table 2_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx
Published 2025“…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …”
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18268
Data Sheet 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.docx
Published 2024“…The Holocene Thermal Maximum (HTM) happened between HCCEs 5 and 4a and was interrupted by HCCE 4c and 4b, coeval, with a significant southward shift of the ITCZ, likely related to cooling in the tropical zone. …”
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18269
Image 3_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18270
3D Nanoscale Structures of Hydrated Polyamide Desalination Membranes Revealed by Cryogenic Transmission Electron Microscopy Tomography
Published 2025“…Our findings reveal significant morphological differences between hydrated and dry membranes, resulting in variations in key structural parameters that impact performance. …”
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18271
Table 3_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …”
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18272
Data Sheet 4_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”
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18273
Data Sheet 5_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”
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18274
Table 4_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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18275
Table 9_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18276
Data Sheet 3_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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18277
Image 2_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif
Published 2025“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”
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18278
Population structure impacts the relationship between the amount of environmental DNA particles and organism abundance
Published 2024“…On the other hand, under the allometric eDNA production, the <i>R</i><sup><em>2</em></sup> values decreased for the populations with broader population size range and broader/heterogeneous mass distribution by using biomass, which was not statistically significant by using ASM.…”
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18279
Image 3_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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18280
Data Sheet 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.pdf
Published 2025“…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …”