Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis حسب Allgayer, Heike

"…RESULTS By CART analysis, Src activity in tumors elevated more than twofold over normal mucosa was significant. Increased Src activity significantly correlated with Dukes stage, pT and pN classification, and increased u-PAR levels (P < 0.001). …"
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Masked phenomenon: renal and cardiovascular complications; review and updates حسب Elmukhtar Habas (14777677)

"…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …"

Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv... حسب Dimassi, Hani

"…On univariate analysis, both the absolute number of positive lymph nodes and the ALNR were significant predictors of OS. On multivariate analysis, only the ALNR remained an independent predictor of OS, with a 2.5-fold increased risk of dying at an ALNR of ≥.25. …"
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Infectious complications with nondaily versus daily infusion of intravenous fat emulsions in non–critically ill adults حسب Btaiche, Imad F.

"…Background: Increased risk for infection has been associated with the administration of intravenous fat emulsion (IVFE). …"
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Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample حسب Fouad Alshaban (6176771)

"…<p dir="ltr">Autism spectrum disorder (ASD) is an increasingly prevalent disorder. Although around 15% of cases are caused by specific genetic causes, most cases involve a complex and variable combination of genetic risk and environmental factors that are not yet identified. …"

Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

"…</p><h3>Materials and Methods</h3><p dir="ltr">A genome-wide DNA methylation study was performed using Illumina Infinium® MethylationEPIC BeadChips on whole blood DNA of 3 male T21 patients with low IQ, 8 T21 patients with high IQ (4 males and 4 females), and 21 age- and sex-matched control samples (12 males and 9 females) in order to determine whether DNA methylation alterations could help explain variation in cognitive impairment between individuals with T21. In view of the increased risk of developing AD in T21 individuals, we additionally investigated the T21-associated sites in published blood DNA methylation data from the AgeCoDe cohort (German study on Ageing, Cognition, and Dementia). …"

Rising blood pressure in Bangladesh حسب Nature Research (16552612)

"…People aged 66 to 74 were found to be significantly more at-risk than those in other age groups. …"

Intermittent nesiritide therapy in outpatients with chronic heart failure حسب Sheikh-Taha, Marwan

"…For this subset of patients, some centers in the United States continue to use periodic ino-tropic therapy on an inpatient or outpatient basis under the rationale of reducing symptoms, hospitalizations, and medical costs, even at the risk of increased mortality. Nesiritide, a human B-type natriuretic peptide, is the first of a new class of agents for the treatment of decompensated HF. …"
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The downsides of information systems security policy compliance efforts حسب Balozian, Puzant

"…Nevertheless, this dissertation challenges that notion and advances a stream of research that suggests increasing security measures may lead to decrease in user productivity, increased user mistrust toward the IT department, increased user frustration, increased user technology avoidance, increased non-malicious volitional security violations and overall may lead to increased security risk, instead of decreasing it. …"
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The Impact of COVID-19 Pandemic on Individuals With Pre-existing Obsessive-Compulsive Disorder in the State of Qatar: An Exploratory Cross-Sectional Study حسب Maryam Siddiqui (5638019)

"…</p><h3>Results</h3><p dir="ltr">Those with the duration of diagnosis of OCD of<10 years showed a statistically significant increase in the mean YBOCS score of 5.54 from pre-pandemic to during pandemic, which was significant at <i>p</i> = 0.006. …"

From past famines to present crises: The epigenetic impact of maternal malnutrition on offspring health in Gaza حسب Mohamed Adil Shah Khoodoruth (14589828)

"…It was shown that first-trimester exposure to severe famine during the Dutch Hunger Winter was associated with increased risk of schizophrenia in offsprings (Hoek et al., 1998). …"

Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19 حسب Matli, Kamal

"…Conclusion The use of combined anticoagulant and antiplatelet agents or TAC alone in hospitalised patients with COVID-19 was associated with a better outcome in comparison to PAC alone without an increase in the risk of major and minor bleeds. Sufficiently powered randomised controlled trials are needed to further evaluate the safety and efficacy of combining antiplatelet and anticoagulants agents or using TAC in the management of patients with COVID-19 infection.…"
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Why does the adverse effect of inappropriate MRI for LBP vary by geographic location? An exploratory analysis حسب Mujahed Shraim (14153145)

"…The aim was to explore whether the known risk of increased length of disability (LOD) associated with eMRI scanning not adherent to guidelines for occupational LBP varies according to patient and area-level characteristics, and the potential reasons for any observed variations.…"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar Shurbaji (9938696)

"…<h3>Background </h3><p dir="ltr">In the last decade, point of care testing (POCT) such as lateral flow immunoassays (LFIA) were developed for rapid TSH measurement. …"

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... حسب SUGATHAN, SANAL

"…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …"
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Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction حسب Aleksandar Jurisic (17052408)

"…Efforts to develop effective treatments to protect pregnancies with abnormal UtA Dopplers would be of significant clinical benefit for mothers and their fetuses.…"

Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy حسب Palavecino, Martin

"…On multivariate analysis, factors that significantly predicted increased red cell transfusion rates were female sex, pre-operative hematocrit <30%, platelet count <100,000/mm3, simultaneous resection of other organs, major hepatic resection, use of the Pringle maneuver, and tumors >10 cm. …"
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0844 Impact of Obstructive Sleep Apnea on patients admitted with Influenza Viral Pneumonia, A Nationwide Study حسب El Labban, Mohamad

"…Introduction There is evidence of increased risk of admission with influenza in patients with untreated obstructive sleep apnea (OSA). …"
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Peroneal tendon dislocation in talus fracture and diagnostic value of fleck sign حسب Ahmed Khalil Attia (10334814)

"…</p><h3>Results</h3><p dir="ltr">Peroneal tendon dislocation was found in ten patients out of 50 (20%). Risk of dislocation increased with severity of the fracture and neck fractures. …"

SGLT-2 inhibitors associated euglycemic and hyperglycemic DKA in a multicentric cohort حسب Fateen Ata (12217764)

"…Infection was the only risk factor with a significant point estimate between the two groups, being more common in hDKA patients (p-value 0.006, RR 2.53, 95% CI 1.07–5.98). …"