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significant decrease » significantly increased (Expand Search)
significant risks » significant risk (Expand Search), significant results (Expand Search), significant role (Expand Search)
risks decrease » sizes decrease (Expand Search), visits decreased (Expand Search), rivers decreased (Expand Search)
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21261
Hypoxia response and tracheogenesis in <i>PGR</i> mutants.
Published 2025“…Homozygous mutant pupae did not show significantly higher expression of <i>bnl</i> until 96 hours APF. …”
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21262
Supplementary Material for: Hemispherotomy for Drug-Resistant Epilepsy in a Low-resource Setting: Surgical Outcomes and Quality of Life in 23 Children Treated in a Hybrid Program i...
Published 2025“…At last follow-up, the majority of children were seizure-free, and all children had decreased seizure frequency. Families reported improved cognitive function, improved QoL and high satisfaction with their decision to pursue this surgery.…”
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21263
Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language...
Published 2025“…In English reports, it matched mainstream AI in lesion analysis (p > 0.05) but excelled in lymph node/pathology metrics (p < 0.05). Task load scores decreased by 38.3% post-implementation (413.90 ± 78.09 vs. 255.30 ± 65.50, t = 26.481, p < 0.001).…”
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21264
Effects of extracts on organs weight.
Published 2025“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”
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21265
Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z...
Published 2025“…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…”
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21266
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
Published 2024“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”
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21267
Table 1_NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patie...
Published 2025“…During the 12-month follow-up of induction therapy, NLR and PLR showed a decreasing trend. Both baseline NLR and SII were positively correlated with baseline UTP and serum creatinine (SCr) levels (r = 0.112-0.148, p< 0.05 for all). …”
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21268
Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes
Published 2025“…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change. …”
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21269
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
Published 2025“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”
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21270
DNA damage protecting effects of PEExCC.
Published 2025“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”
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21271
<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation
Published 2025“…We further explored the role of <i>StiP</i> in host blood environment adaptation and found that 263<i>ΔStiP</i> displayed 3.12-fold reduced HeLa cell adhesion, 3.74-fold lower HeLa cell invasion, 1.92-fold decreased intra-macrophage survival, and 50% reduced serum resistance versus wild-type 263 (WT263), collectively indicating that <i>StiP</i> is critical for host blood environment adaptation in invasive <i>S</i>. …”
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21272
Data Sheet 1_Endophytic and antagonistic Bacillus amyloliquefaciens 8SE-IF1-derived nanoparticles encumber phytopathogenic oomycetes, fungi, bacteria, and viruses with enhanced gro...
Published 2025“…The water-diffusible extract (WDE) of Ba-8SE-IF1 significantly inhibited the mycelial growth of Pythium aphanidermatum (44.6%), Phytophthora nicotianae (60.1%), Fusarium oxysporum f. sp. lycopersici (65.5%), and Colletotrichum gloeosporioides (66.7%) in poisoned food assays; the growth of Ralstonia solanacearum and Xanthomonas campestris in the agar well method (inhibition zones of 20.25 mm and 28.52 mm, respectively); and decreased the symptoms produced by tomato spotted wilt virus (TSWV) in local lesion host (68.3%) and tomato leaf curl New Delhi virus (ToLCNDV) in tomato plants (66.1%). …”
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21273
Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe...
Published 2025“…AMH sampling on different cycle days showed only modest effects from minor fluctuations; only substantial AMH decreases significantly affected prediction accuracy. …”
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21274
Figure 2 from Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in <i>EGFR</i>- and <i>KRAS</i>-Mutant Lung Cancer
Published 2025“…<p>PRMT1 knockdown decreases persistence in STAT1-high <i>EGFR</i><sup><i>mut</i></sup> and <i>KRAS</i><sup><i>G12C</i></sup> lung cancer cell lines. …”
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21275
Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs
Published 2024“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”
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21276
Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
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21277
Table 6_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …”
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21278
Data Sheet 2_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.docx
Published 2025“…The primary objectives of this optimization process include reducing nurse workload, improving job satisfaction, and decreasing turnover rates, all of which facilitate improved patient outcomes.…”
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21279
Data Sheet 1_Mobility status, nutritional intervention and meal eaten are associated with discharge home: the nutritionDay study in China.docx
Published 2025“…In multivariable models accounting for other parameters, patients receiving dietary nutrition had a 0.45 (95% CI [0.36–0.55], p < 0.001) lower probability of reduced mobility compared with patients receiving artificial nutrition, and patients who ate their meals completely had a 0.34 (95% CI [0.28–0.41], p < 0.001) decreased chance of reduced mobility compared with those with incomplete meal intake.…”
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21280
Data Sheet 1_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.pdf
Published 2025“…The primary objectives of this optimization process include reducing nurse workload, improving job satisfaction, and decreasing turnover rates, all of which facilitate improved patient outcomes.…”