Data Sheet 1_Safety assessment of tolvaptan: real-world adverse event analysis using the FAERS database.docx by Peiyang Cao (10808613)

“…</p>Conclusion<p>While tolvaptan provides therapeutic benefits, it poses a risk of significant adverse reactions. Clinicians should closely monitor the occurrence of events related to hepatobiliary disorders, renal and urinary disorders, metabolic and nutritional disorders, as well as benign, malignant, and indeterminate tumors during its clinical use.…”

Data Sheet 1_Does chlorhexidine improve periodontal health and bacterial profiles in patients with special health care needs? A systematic review and meta-analysis.docx by Deepak Sharma (131639)

“…Gingival inflammation also decreased significantly across studies (mean difference = −0.214; 95% CI: −0.306 to −0.121; P < .001), with 0.2% CHX formulations demonstrating the most consistent improvement.…”

Table_1_Construction of a risk screening and visualization system for pulmonary nodule in physical examination population based on feature self-recognition machine learning model.X... by Fang Tian (360682)

“…</p>Results<p>Multivariable analysis identified older age, smoking or passive smoking, high psychological stress within the past year, occupational exposure (e.g., air pollution at the workplace), presence of chronic lung diseases, and elevated carcinoembryonic antigen levels as significant risk factors for pulmonary nodules. The feature self-recognition machine learning model further highlighted age, smoking or passive smoking, high psychological stress, occupational exposure, chronic lung diseases, family history of lung cancer, decreased albumin levels, and elevated carcinoembryonic antigen as key predictors for early pulmonary nodule risk, demonstrating superior performance.…”

Table 1_Clinical outcomes and psychosomatic correlates of integrative inpatient care based on Traditional Korean Medicine for acute neck and low back pain following traffic acciden... by Yohwan Kim (5482454)

“…Greater reductions in axial pain, as measured by Numeric Rating Scale scores, were significantly associated with decreases in scores on the Beck Anxiety Inventory, Fatigue Severity Scale, Patient Health Questionnaire-9, and Insomnia Severity Index in regression analyses adjusted for clinical and demographic covariates. …”

Effects of task optimization on pareidolia representations in CNNs. by Pranjul Gupta (20623949)

“…Conversely, in CNNs lacking object categorization training (Panels B, C), this similarity was weak, only reaching significance at early layers, and decreased across layers. …”

Table 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc by Meizhi Liu (21898892)

“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”

DataSheet2_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf by Xiaoqin Zhang (517854)

“…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …”

Data Sheet 2_Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels.pdf by Shuang Li (146392)

“…At the national level, ASRs consistently decreased with higher SDI.</p>Conclusion<p>This study highlights the substantial burden of NRLC at global, regional, and national levels. …”

Data Sheet 1_Divergent profiles of rhizosphere soil carbon and nitrogen cycling in Pinus massoniana provenances with different types of carbon storage.docx by Zichen Huang (6587885)

“…</p>Results<p>Our findings revealed a significant increase in the relative abundance of Acidobacteriota and Ascomycota by 23 and 61%, respectively, whereas Basidiomycota significantly decreased by 8% in the rhizosphere of P. massoniana provenances with high carbon storage compared with those with low carbon storage. …”

Table 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx by Ilmari Pyykkö (2855153)

“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”

Image2_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG by Jacob Raiten (20021262)

“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …”

Table2_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.xlsx by Vineeta Pandey (10043698)

“…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …”

Table1_Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy.docx by Chiara Ceolin (19553155)

“…Introduction<p>Higher stress levels are linked to increased body fat and decreased bone density, effects that can be exacerbated by lifestyle choices. …”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…There was no significant difference between aqueous RBP3 levels in those with type 1 or type 2 diabetes. …”

Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx by Cassidy Jones (22301638)

“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”

Divergent gene expression in <i>D. sechellia.</i> by Daehan Lee (5043377)

“…<p><b>(A)</b> Histogram of the frequency of <i>D. sechellia</i>-specific DEGs across 94 cell types, arranged by decreasing DEG number. The remaining 13 cell types with no DEGs are not shown. …”

Amplifying key words’ intensity promotes memory (Liu et al., 2025) by Zhenxu Liu (1372929)

“…Heart rate and skin conductance level of the subjects decreased with amplification of key word intensity in the 9-dB group, which indicated that this promoted the memory effect by enhancing attention.…”

Data Sheet 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.docx by Yiwen Li (354034)

“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”

Data Sheet 1_Efficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and m... by Pedro de Padua G. Amatto (20981201)

“…The pooled analysis showed significant reductions in WHO scores and oral pain compared to placebo. …”