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161
Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”
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162
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …”
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163
Renal Function Decline in Recipients and Donors of Kidney Grafts
Published 2015“…Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. …”
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164
Ultraliser: a framework for creating multiscale, high-fidelity and geometrically realistic 3D models for <i>in silico</i> neuroscience
Published 2022“…Ultraliser is publicly released under the GNU GPL3 license on GitHub (<a href="https://github.com/BlueBrain/Ultraliser" target="_blank">BlueBrain/Ultraliser</a>).</p><h3>Significance</h3><p dir="ltr">There is crystal clear evidence on the impact of cell shape on its signaling mechanisms. …”
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165
Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon
Published 2018“…Recurrent dislocation, being a major reason for revision total hip arthroplasty (THA), was found to decrease significantly using dual mobility cup (DMC) compared to standard cups (SC), and that in both primary and revision THA. …”
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166
Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
Published 1991“…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …”
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167
Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study
Published 2019“…By decreasing the density of water molecules inside the membrane, we observed that water molecules form a droplet through a hydrogen bond with each other in the hydrophobic environment that stacked graphene sheets create. …”
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168
Factors Determining SMEs Intention to Access Alternative Financing in Emerging Markets: Evidence from the UAE
Published 2023“…The primary objective of this study is to investigate the factors that may shape SMEs' inclination to adopt alternative finance in emerging markets, with a particular emphasis on the UAE market. …”
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169
Orofacial Clefts
Published 2021“…We found no significant differences in the proliferative abilities of the patient-derived cells and the healthy cells. …”
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170
Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…On the other hand, decreased volatility hurts exports of Japan. As for the long-run effects of exchange rate volatility on imports, we found that increased volatility boosts imports of Korea. …”
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171
The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
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doctoralThesis -
172
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Similarly, we observed decreased in vivo ectopic bone formation. …”
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173
An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health
Published 2024“…We observed that bone area, bone mineral content, and bone mineral density were slightly lower in the Diabetes group across almost all body parts, but the difference against the control group was not statistically significant except in T12, troch and trunk area. …”
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174
Determinants of Off-Balance Sheet Business in the Case of GCC Banking Sectors during Covid-19
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doctoralThesis -
175
The impact of nursing education curriculum and workforce preparation on students’ critical thinking, moral reasoning and evaluate their perspectives on cultural sensitivity in UAE...
Published 2020“…The danger of incorrect nurse’s decisions on the patient’s health has become a significant threat for both the nursing students and graduates. …”
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176
Unsustainability in emergent systems
Published 2017“…We propose a framework of corresponding mitigation options as a roadmap for improving the sustainability of the system, namely by reducing the reliance on fossil fuels, decreasing pollutants and Greenhouse Gas (GHG) emissions, reducing mobility costs and increasing passenger safety.…”
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177
Patterns of the superficial veins of the cubital fossa
Published 2017“…Results Meta-analysis showed that “N” shaped arrangement type was the commonest pattern (≈44–60%) followed by “M” shaped arrangement (≈20–25%). …”
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178
Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas...
Published 2021“…Among females, none of these 12 countries had significant decreases in prevalence of chewing tobacco use, whereas seven of 12 countries had a significant decrease in the prevalence of tobacco smoking use for the period. …”
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179
When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
Published 2021“…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …”
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180
Stress Management Using Physiological Signals and Audio Stimulation
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doctoralThesis