Data Sheet 1_Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts.doc حسب Arbi Guetat (3068151)

"…</p>Results<p>Oral administration of hydroethanolic extract of S. deserti at 200 and 400 mg/kg for 14 days significantly decreased blood glucose and restored the hepatic and renal function by reducing the levels of ALT, AST, ALP, GGT, LDH, urea and creatinine. …"

Image 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

"…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …"

Table1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.XLSX حسب Cong Zhang (582922)

"…</p>Results<p>The results revealed that IBD (OR = 1.049, 95% CI = 1.010–1.090, p = 0.013) and ulcerative colitis (UC) (OR = 1.057, 95% CI = 1.013–1.102, p = 0.011) were significantly associated with an increased risk of AP. …"

Table3_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg حسب Yun Zhou (308977)

"…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …"

Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

"…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …"

Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

"…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …"

Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

"…Introduction<p>Increasing evidence highlights the pivotal role of RNA methylation and miRNAs in hepatocellular carcinoma (HCC). …"

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

"…Upregulation of DYNLT3 expression markedly decreased the expression of Wnt signaling pathway-related proteins (Dvl2, Dvl3, p-LRP6, Wnt3a, Wnt5a/b, Naked1, Naked2, β-catenin and C-Myc) and EMT-related proteins (N-cadherin, SOX2, OCT4, vimentin and Snail), and increased the expression of E-cadherin and Axin1. …"

Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx حسب Bart J. F. Keijser (16884185)

"…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"

Table 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"

Image 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"

Image 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif حسب Marcela Rios-Carlos (22759823)

"…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …"

Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf حسب Mengyuan Dai (9747317)

"…OA model demonstrated that EGCG treatment significantly promoted cartilage repair and increased Pla2g2a expression. …"

Image 4_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Table 2_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"

Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx حسب Wu Di (11561998)

"…</p>Results<p>TP treatment significantly reduced osteoclastogenesis in both co‐culture and conditioned medium systems. …"

Muscles influence motoneuron at NMJ during the critical period, but motoneuron do not affect GluR composition in muscles. حسب Daniel Sobrido-Cameán (5049743)

"…<p><b>(A)</b> Heat stress experienced during the embryonic critical period (32°C vs. 25°C control) leads to decreased postsynaptic GluRIIA. Simultaneous genetic manipulation of aCC motoneuron during embryonic stages does not affect GluRIIA in muscles. …"

Data Sheet 6_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.pdf حسب Paolo Romania (399007)

"…Among them, the placenta-specific 1 (PLAC1) gene stood out, as its inhibition conferred the greatest protection to target cells from NK cell lysis, while overexpression of PLAC1 significantly increased NK cell degranulation. Importantly, PLAC1 was found to interact with NKAR fusion proteins, including NKG2D, DNAM1 NKp44 and NKp30, suggesting its potential involvement in NK cell function. …"