mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t... حسب Shanhe Liu (5251313)

"…In LSCs, <i>BCL2</i> mRNA level significantly decreased (p = 0.0102) and <i>CDKN1B</i> level significantly increased using 75 µM CoCl₂ treatment. …"

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Data Sheet 1_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf حسب Shiqiu Xiong (238109)

"…Introduction<p>Anomalous congenital bands are a rare cause of intestinal obstruction, with only five previously reported cases involving duodenal obstruction. We present a fifth case of duodenal obstruction due to two congenital bands and provide a comprehensive literature review summarizing the clinical features of this condition.…"

Data used in the simulations. حسب Anna Ferretto (17473110)

"…However, there is a significant knowledge gap regarding how current and future forest management practices will affect carbon turnover time. …"

DataSheet4_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…"

Data Sheet 1_Ribosomal protein L9 is a potential therapeutic target for B-ALL through the activation of the p53 signaling pathway.docx حسب Xinxin Li (281237)

"…Although recent advancements have highlighted the pivotal role of ribosomes in the progression of B-ALL, the specific function of ribosomal protein L9 (RPL9), a key component of ribosomal structural protein, still unclear. In this study, we observed a significant upregulation of RPL9 in human B-ALL cells compared to normal B cells, suggesting RPL9’s potential key role in B-ALL progression. …"

Renal function and risk of dementia: a Mendelian randomization study حسب Haowen Huang (1430386)

"…At the stratum of genetic susceptibility, we tested the causal relationship between variations index in renal function and the occurrence of dementia. …"

Data Sheet 1_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx حسب Sarah Mendorf (11632098)

"…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…"

DataSheet7_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf حسب Yongming Du (807059)

"…</p>Results<p>The MR analyses revealed that genetically determined coeliac disease (CeD) (OR = 1.124, 95% CI 1.033-1.224, P = 0.007), vitiligo (OR = 1.092, 95% CI 1.003-1.188; P = 0.042), systemic lupus erythematosus (SLE) (OR = 1.122, 95% CI 1.030-1.223, P = 0.008), and selective immunoglobulin A deficiency (SIgAD) (OR = 0.866, 95% CI: 0.776-0.967, P = 0.011) exhibited significant causal relationships with POI. We also found suggestive evidence of positive effect of Addison’s disease (AD) towards POI (OR_5e-6 = 1.076, 95% CI 1.002-1.154, P = 0.043).…"

DataSheet1_Pressure-tolerant survival mechanism of Schizophyllum commune 20R-7-F01 isolated from deep sediments 2 kilometers below the seafloor.csv حسب Mengshi Zhao (20157978)

"…By assessing the cell viability, biomass, and cell wall thickness changes of strain 20-7-1 under different HHP conditions, we observed that, compared to 0.1 MPa, strain 20-7-1 exhibited slower growth rates and decreased cell viability at 15 MPa and 35 MPa, yet demonstrated significant pressure tolerance. …"

Data Sheet 2_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf حسب Shiqiu Xiong (238109)

"…Introduction<p>Anomalous congenital bands are a rare cause of intestinal obstruction, with only five previously reported cases involving duodenal obstruction. We present a fifth case of duodenal obstruction due to two congenital bands and provide a comprehensive literature review summarizing the clinical features of this condition.…"

Image 1_Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.jpeg حسب Bhaswati Roy (2802559)

"…</p>Results<p>At baseline, obese patients had significant brain tissue changes seen in MRI and decreased cognitive scores compared to controls (MoCA 26 vs 28, P = 0.017). …"

Image 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf حسب Jinque Luo (9645983)

"…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …"

Data Sheet 2_Red mite (Panonychus citri) attack amplifies citrus rootstock-driven responses in physiological and biochemical traits, VOC emission, and expression of defence-related... حسب Tommy Rioja (22179742)

"…<p>Citriculture faces significant constraints in expanding into new environments and agroecological zones. …"

Image 1_Comparative analysis of gut microbiota in metabolic syndrome and obese children from Southeastern China.jpeg حسب Jingjing Wang (140791)

"…At the class and genus levels, we found that the relative abundance of c_Gammaproteobacteria increased with weight, whereas c_Bacteroidia and g_Bacteroides decreased. …"

Thermodynamic properties of non-azeotropic refrigerant heat pumps under full operating conditions with non-phase-change heat sinks and heat soucres حسب Hemin Hu (21488860)

"…<p>When using pure refrigerants in heat pump, a significant temperature mismatch arises between hot and cold fluids within the evaporator and condenser, adversely impacting the thermal efficiency of system. …"

Data Sheet 2_Screening of neurotransmitter receptor modulators reveals novel inhibitors of influenza virus replication.pdf حسب Yarou Gao (20620991)

"…In a mouse model of lethal influenza, isoxsuprine significantly decreased lung viral titers, mitigated pulmonary inflammation, and enhanced survival rates. …"

Data Sheet 1_Morphophysiological and transcriptomic analyses during the development of microspores and megaspores in Orobanche coerulescens.docx حسب Kelin Cui (20936231)

"…We also investigated the key regulatory genes in the metabolic pathways of phytohormones that are closely related to the development of microspores and megaspores using transcriptome sequencing technology.…"

Data Sheet 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.pdf حسب Jinque Luo (9645983)

"…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …"