Search alternatives:
significant sharp » significant short (Expand Search), significant shape (Expand Search), significant gap (Expand Search)
sharp increase » year increase (Expand Search)
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
bins decrease » point decrease (Expand Search), nn decrease (Expand Search)
significant sharp » significant short (Expand Search), significant shape (Expand Search), significant gap (Expand Search)
sharp increase » year increase (Expand Search)
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
bins decrease » point decrease (Expand Search), nn decrease (Expand Search)
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compound 206 (1μM) significantly increased spheroid size relative to DMSO + CSE 3% control bronchospheres. …”
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Overexpression of Gαq decreases cell number and cell size.
Published 2021“…Overexpression of Gαq in the pouch results in a decrease in total wing area, cell number and cell size. 10 samples were analyzed per condition. …”
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Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss <i>in vivo</i>
Published 2019“…Furthermore, the level of neuronal-specific BIN1 isoform 1 protein is decreased in sporadic AD cases in parallel with neuronal loss, despite an overall increase in BIN1 total mRNA. …”