Showing 101 - 120 results of 6,545 for search '(( significant shifts decrease ) OR ( significant ((we decrease) OR (teer decrease)) ))', query time: 0.37s Refine Results
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    Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

    Published 2025
    “…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
  5. 105

    Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

    Published 2025
    “…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
  6. 106

    Discovery of NP3-742: A Structurally Diverse NLRP3 Inhibitor Identified through an Unusual Phenol Replacement by Juraj Velcicky (2201350)

    Published 2025
    “…Initial indole analog <b>7</b> demonstrated a robust in vivo IL-1β inhibition, but also a significant hERG inhibition. Decreasing lipophilicity led to the discovery of <b>NP3-742</b>, demonstrating a favorable overall profile including diminished hERG inhibition and in vivo efficacy in a mouse peritonitis model.…”
  7. 107

    Variables of trees located at coordinates . by Alexandra M. Campbell (3284094)

    Published 2025
    “…<i>Tillandsia utriculata</i> has been classified as endangered in Florida where its population has decreased significantly due to predation by the invasive Mexican weevil <i>Metamasius callizona</i>. …”
  8. 108

    Global parameters and variables for the model. by Alexandra M. Campbell (3284094)

    Published 2025
    “…<i>Tillandsia utriculata</i> has been classified as endangered in Florida where its population has decreased significantly due to predation by the invasive Mexican weevil <i>Metamasius callizona</i>. …”
  9. 109

    Variables of patch located at coordinates . by Alexandra M. Campbell (3284094)

    Published 2025
    “…<i>Tillandsia utriculata</i> has been classified as endangered in Florida where its population has decreased significantly due to predation by the invasive Mexican weevil <i>Metamasius callizona</i>. …”
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    MRSP Data collected in March 2018. by Alexandra M. Campbell (3284094)

    Published 2025
    “…<i>Tillandsia utriculata</i> has been classified as endangered in Florida where its population has decreased significantly due to predation by the invasive Mexican weevil <i>Metamasius callizona</i>. …”
  11. 111

    Table 1_NSAID use may decrease serum Klotho levels.docx by Jingchao Yan (14079168)

    Published 2025
    “…Subgroup analyses did not reveal any statistically significant interactions.</p>Conclusion<p>Contrary to previous speculations, the use of NSAIDs is associated with a decrease in serum Klotho levels.…”
  12. 112

    Characteristics of Study Participants. by Alix Boisson-Walsh (17847176)

    Published 2025
    “…<div><p>The COVID-19 pandemic negatively impacted routine immunizations worldwide, decreasing confidence in vaccination programs. We used mixed methods to examine changes in vaccine confidence from before to during the pandemic in HBV-negative adults in Kinshasa who were exposed to HBV in the household, and eligible for HBV vaccination. …”
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    Predictive Significance of Glycosyltransferase-Related lncRNAs in Endometrial Cancer: A Comprehensive Analysis and Experimental Validation by Xiaoyu Shen (4715430)

    Published 2025
    “…And the low-risk cohort exhibited increased immune infiltration and decreased tumor purity. Additionally, significant differences in tumor mutation profiles were observed, with the tumor mutation burden (TMB) being higher in the low-risk cohort, suggesting a potentially better response to immunotherapy. …”
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