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significant source » significant burden (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
larger decrease » marked decrease (Expand Search)
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6821
Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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6822
Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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6823
Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx
Published 2024“…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”
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6824
Image 1_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg
Published 2024“…From 2015 to 2020, the number of areas with balanced supply and demand of ecosystem services in the Yangtze River Economic Belt decreases and the number of areas with unbalanced supply and demand increases, which is related to the changes in the level of economic development and land use patterns. 3). …”
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6825
Table 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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6826
DataSheet1_Diphenyl diselenide protects against diabetic kidney disease through modulating gut microbiota dysbiosis in streptozotocin-induced diabetic rats.docx
Published 2024“…</p>Results<p>The results showed DPDS and metformin improved the DKD in STZ rats, as evidenced by decreased blood glucose, BUN, urine volume, urine microalbumin, urinary β2 microglobulin, and improvement of renal pathological morphology. …”
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6827
Table 1_Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, paralle...
Published 2025“…Therapy adherence- and health literacy-related DRPs decreased significantly by ~60% and ~64%, respectively. …”
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6828
Supplementary Material for: Focus on the Blind Spot of Stone Disease: Analysis of Lower Urinary Tract Stone Interventions from 2006 to 2020 using German nationwide inpatient data.
Published 2024“…Methods We analyzed data from the nationwide German hospital billing database from 2006 to 2020. The significance of changes over time was evaluated via linear regression analysis. …”
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6829
<i>map3k1</i> inhibition causes <i>ovo+</i> eye progenitors to undergo premature terminal differentiation.
Published 2025“…The number of undifferentiated <i>ovo</i><sup>+</sup> eye progenitors did not change significantly in <i>map3k1(RNAi)</i> worms at 0, 2, 5, and 8dpa. …”
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6830
Effects of frequency difference, tactile conditions, and replicability.
Published 2025“…Participants’ perception of segregation was significantly lower in Tact B compared to Tact A. <b>C:</b> The change in proportion segregated compared to reference condition Tact Off.…”
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6831
Data Sheet 1_Mitigating ammonium and nitrate leaching in rice-wheat crop rotation: efficacy of neem coated urea and compost co-application.pdf
Published 2025“…Introduction<p>Leaching losses of applied N are an indirect source of nitrous oxide (N<sub>2</sub>O) emission, a major greenhouse gas emitted from fertilized soils. …”
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6832
Data Sheet 2_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.docx
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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6833
Data Sheet 1_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.zip
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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6834
Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx
Published 2025“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”
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6835
Table 2_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.docx
Published 2025“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”
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6836
Image 2_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Introduction<p>The global burden of lead exposure-related ischemic stroke poses a significant concern for public health, and this study aimed to comprehensively analyze the current situation, the change patterns, and forecast potential future trends associated with this critical issue.…”
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6837
Table 1_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.docx
Published 2025“…Introduction<p>The global burden of lead exposure-related ischemic stroke poses a significant concern for public health, and this study aimed to comprehensively analyze the current situation, the change patterns, and forecast potential future trends associated with this critical issue.…”
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6838
Image 3_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Introduction<p>The global burden of lead exposure-related ischemic stroke poses a significant concern for public health, and this study aimed to comprehensively analyze the current situation, the change patterns, and forecast potential future trends associated with this critical issue.…”
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6839
Image 1_The global burden of lead exposure-related ischemic stroke: based on Bayesian age-period-cohort analysis.png
Published 2025“…Introduction<p>The global burden of lead exposure-related ischemic stroke poses a significant concern for public health, and this study aimed to comprehensively analyze the current situation, the change patterns, and forecast potential future trends associated with this critical issue.…”
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6840
Table 1_Molecular epidemiological characteristics of pertussis in a pediatric hospital in Jinan City, China, 2022 to 2024.docx
Published 2025“…No significant change occurred in Streptococcus pneumoniae co-infections (P<sub>trend</sub> > 0.05).…”