Data Sheet 1_Investigating the underlying mechanisms of the ethanol extract of saussureae involucratae herba in anti-rheumatoid arthritis effect based on sphingolipidomics.pdf حسب Pingyuan Chi (21563069)

"…In cell assays, SIE significantly decreased the protein levels of TNF-α and IL-6 (both P < 0.01) in LPS-stimulated RAW 264.7 cells. …"

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX حسب Mingming Zhao (760369)

"…Immunocoprecipitation indicated that VPA significantly increased the acetylation level of FXR, and the application of agonist SRT1720 can antagonize the acetylation of FXR by VPA.…"

Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... حسب Menekse Oeztuerk (20756606)

"…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …"

Image 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati... حسب Menekse Oeztuerk (20756606)

"…Lipidomic analysis highlighted substantial alterations in lipid composition, with significant decreases in sphingomyelins, phosphatidylethanolamine, and phosphatidylcholine, reflecting disruptions in lipid metabolism and membrane integrity. …"

Supplementary Material for: Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis حسب figshare admin karger (2628495)

"…Inhibiting NETosis with GSK484 reduced CitH3 levels in IgAN mice and improved clinical outcomes, including decreased proteinuria and increased serum albumin. …"

Supplementary file 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …"

Table 1_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.docx حسب Chao Li (145513)

"…Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …"

Table 2_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... حسب Qi Sun (127)

"…</p>Results<p>IP significantly lowed fasting blood glucose and blood insulin levels. …"

Supplementary file 2_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …"

Table 1_Ipriflavone ameliorates intervertebral disc degeneration by inhibiting osteoporosis of vertebral body and pyroptosis of the nucleus pulposus in instability of lumbar spine... حسب Qi Sun (127)

"…</p>Results<p>IP significantly lowed fasting blood glucose and blood insulin levels. …"

Supplementary file 3_Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.tif حسب Chao Li (145513)

"…Results from transcriptome sequencing analysis and experiments identified significantly decreased SRSF1 level in drug resistant cells after CYT treatment. …"

Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx حسب Yanni Lan (9092615)

"…</p>Methods<p>We utilized comprehensive data sources from the Global Health Data Exchange (GHDx). …"

Swimming endurance training reduces T-wave amplitude and area in <i>Mib1</i>^<i>flox</i><i>;Tnnt2</i>^<i>Cre</i> mice. حسب Vítor S. Fernandes (21262991)

"…<i>*P</i> < 0.05 Results represent mean±SD of 7-5 animals per genotype.</p>…"

Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden... حسب Matej Stuhec (5643284)

"…</p>Results<p>The study included 100 inpatients with a mean age of 78.1 years (SD = 6.78). The total number of medications decreased by 6.6% (from 1,144 to 1,068; p < 0.001), with an acceptance rate of 59.2%. …"

<b>Seizure-induced changes in cytokine expression and dysregulation of plasminogen activation and IGF systems following kainic acid administration in rats</b> حسب Elena Suleymanova (22195777)

"…We also observed disruption of the IGF system, characterized by decreased IGFBP-5 protein levels in the hippocampus and downregulation of <i>Igfbp5</i> mRNA in both hippocampus and cortex. …"

Data Sheet 1_Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models... حسب Shreshta Jain (12274885)

"…Cognitive function was assessed using the Morris water maze, while brain tissues were examined for oxidative stress markers, autophagy indicators, senescence activity, and amyloid-β levels.</p>Results<p>Decanoic acid significantly improved learning and memory performance, enhanced antioxidant enzyme activity (superoxide dismutase, reduced glutathione, catalase), promoted autophagy by inhibiting mTOR, reduced cellular senescence (β-galactosidase-positive cells), and decreased amyloid-β toxicity. …"

Image 1_Effects of traditional Chinese exercises on post-stroke depression: a meta-analysis of randomized controlled trials.pdf حسب Yan Li (23143)

"…Specifically, HAMD scores decreased [SMD = −1.40, 95% CI (−1.88, −0.92), p < 0.00001], treatment efficacy improved [OR = 3.74, 95% CI (1.69, 8.28), p = 0.001], FMA scores increased [MD = 6.22, 95% CI (4.12, 8.32), p < 0.00001], and BI levels rose [MD = 4.95, 95% CI (2.96, 6.93), p < 0.00001]. …"

Table 3_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx حسب Zhixun Bai (14021787)

"…Background<p>Acute viral hepatitis (AVH) remains a global health concern, with significant variations in incidence, mortality, and DALYs across different regions, age groups, genders, and socioeconomic levels. …"

Data Sheet 1_Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites.docx حسب Tingyu Yang (10686507)

"…Additionally, OJO significantly reduced acetic acid and propanoic acid levels. …"

Table 2_Global, regional, and national burden of acute hepatitis (1990–2021): a systematic analysis of the global burden of disease in 2021.xlsx حسب Zhixun Bai (14021787)

"…Background<p>Acute viral hepatitis (AVH) remains a global health concern, with significant variations in incidence, mortality, and DALYs across different regions, age groups, genders, and socioeconomic levels. …"