Higher serum leptin level in women than in nen with type 1 diabetes by Azar, Sami T.

“…In humans, serum leptin concentrations are increased in relation to increased body fat content. …”
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The effect of GLP-1R agonists on the medical triad of obesity, diabetes, and cancer by Shahad Sabaawi Ibrahim (21842273)

“…<p dir="ltr">Glucagon-like peptide-1 receptor (GLP-1R) agonists have garnered significant attention for their therapeutic potential in addressing the interconnected health challenges of diabetes, obesity, and cancer. …”

Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien... by Shayista Akbar (14442117)

“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…The effects of increased endogenous ceramides could be offset by sphingosine 1-phosphate (S1P), a prosurvival by-product of ceramide metabolism. …”
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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes by Fakhoury, H.

“…PBA significantly increased GLUT1 but not GLUT4 total protein expression. …”
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells by Homaidan, Fadia R.

“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. …”
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Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes by Rizk, Sandra

“…Purpose: The present study investigates the effect of a cell-free fraction of kefir on CEM and Jurkat cells, which are human T-lymphotropic virus type I (HTLV-1)-negative malignant T-lymphocytes. Methods: Cells were incubated with different kefir concentrations. …”
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Challenges and practices identification in complex outsourcing relationships: A systematic literature review by Ghulam Murtaza Khan (12024573)

“…<p dir="ltr">Complex IT outsourcing relationships aptitude several benefits such as increased cost likelihood and lowered costs, higher scalability and flexibility upon demand. …”

System dynamics modeling for mitigating energy use and CO2 emissions of freight transport in Lebanon by Haddad, Marc

“…Previous studies showed that significant reductions in energy use and emissions can be achieved from combining mitigation strategies that improve engine technology for cars and increase the use of public transport. …”
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The effects of Social Determinants of Health on Type 2 Diabetes Outcomes (A1C) by Awad, Nathalie

“…Diabetes duration of 5-10 years increased the odds of having uncontrolled A1C by more than 3 folds. …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009) by Daher, Jalil Y.

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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data by Mohanad Shehadeh (17860691)

“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”

Effects of information and communication technology on total-factor carbon emission efficiency and the health co-benefits by Jingying Linghu (22337614)

“…The results suggest that ICT significantly and positively impacts the TFCEE. Specifically, for every 10 per cent increase in the internet development index, the TFCEE increases by 0.11 per cent. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). Concurrently, Ex-4 significantly lowered the expression levels of De novo lipogenesis genes such as SREBP-1, SCD-1and ACC. …”

Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in... by Goran Petrovski (129836)

“…HbA1c decreased from 8.6 ± 1.7% (70 ± 18.6 mmol/mol) at baseline, to 6.5 ± 0.7% (48 ± 7.7 mmol/mol) at the end of the study (<i>p</i> = 0.001). …”

RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…This was supported by our findings of high EC marker expression levels in <i>RFX3</i> KO EPs and islets. In addition, RFX3 loss led to smaller islet organoids, elevated thioredoxin-interacting protein levels and increased apoptosis in EPs and islets. …”

A photoactivatable Ru (II) complex bearing 2,9-diphenyl-1,10-phenanthroline by Mansour, Najwa

“…A significant increase in cell rounding and detachment, loss of membrane integrity, ROS accumulation and DNA damage was observed. …”
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Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis by Susie S. Y. Huang (2824502)

“…Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …”

Transcriptome analysis of Escherichia coli K1 after therapy with hesperidin conjugated with silver nanoparticles by Masri, Abdulkader

“…Of note, the expression levels of cation efflux genes (cusA and copA) and translocation of ions, across the membrane genes (rsxB) were found to increase 2.6, 3.1, and 3.3- log FC, respectively. Significant regulation was observed for metabolic genes and several genes involved in the coordination of flagella. …”
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