Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. حسب Sara Hijazi (21656615)

"…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …"

qPCR analysis of CK8 knockdown affecting Clauding-1 mRNA expression. حسب Wen Wen Zheng (17721404)

الموضوعات:

Molecular-docking simulation of the TsSPc–CK8 complex in Caco-2 cells. حسب Wen Wen Zheng (17721404)

الموضوعات:

CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. حسب Wen Wen Zheng (17721404)

الموضوعات:

Detail of the personalized-enhanced GCN. حسب Yuanming Ding (12842858)

الموضوعات:

Enhanced multi-component module. حسب Yuanming Ding (12842858)

الموضوعات:

The architecture of the TCBiL. حسب Yuanming Ding (12842858)

الموضوعات:

Detail of the encoder. حسب Yuanming Ding (12842858)

الموضوعات:

Detail of the Fourier transform. حسب Yuanming Ding (12842858)

الموضوعات:

Detail of the decoder. حسب Yuanming Ding (12842858)

الموضوعات:

Encoder-decoder architecture. حسب Yuanming Ding (12842858)

الموضوعات:

Dataset description. حسب Yuanming Ding (12842858)

الموضوعات:

PeMSD8. حسب Yuanming Ding (12842858)

الموضوعات:

AUT00201 (1 µM) can rescue AP width in cuprizone mice. حسب Sara Hijazi (21656615)

"…In the responsive cells from cuprizone mice (red) a significant increase in PV interneuron firing frequency at lower current steps (gray) was observed (<i>group x current two-way repeated measures: n = 8 cells from 4 mice: p = 0.05287; AUT00201 effect: F(1,60) = 5.050, *p = 0.0457. …"

Comparison between juvenile and adult demyelination. حسب Sara Hijazi (21656615)

"…Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …"

Raw data 16–20. حسب Fateme Khorramroo (18086501)

"…These results should be considered when using a wide step width as a gait retraining method for managing flat-footed individuals.…"

Demographics, SD= Standard Deviation. حسب Fateme Khorramroo (18086501)

"…These results should be considered when using a wide step width as a gait retraining method for managing flat-footed individuals.…"

Raw data 6–9 and 15. حسب Fateme Khorramroo (18086501)

"…These results should be considered when using a wide step width as a gait retraining method for managing flat-footed individuals.…"

Raw data 1–5. حسب Fateme Khorramroo (18086501)

"…These results should be considered when using a wide step width as a gait retraining method for managing flat-footed individuals.…"

Raw data 10–14. حسب Fateme Khorramroo (18086501)

"…These results should be considered when using a wide step width as a gait retraining method for managing flat-footed individuals.…"