Overexpression of TNFAIP9 inhibited the TGF-β-induced fibrosis in HK-2 cells. by Ying Chen (9697)

TNFAIP9 expression was increased in mice with chronic kidney disease (CKD) induced by 5/6 nephrectomy (Nx). by Ying Chen (9697)

Overexpression of TNFAIP9 counteracted the renal damage caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 inhibited the TNF-α-induced inflammation in HK-2 cells. by Ying Chen (9697)

Additional within-case comparison information. by Ryan J. Treves (13527735)

“…While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

POTW sample summary. by Ryan J. Treves (13527735)

“…While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

Characteristics of the participants. by Kensaku Sasayama (741571)

“…Overall physical activity levels decreased at follow-up compared to baseline. However, the contribution of commuting school activities to overall physical activity significantly increased at follow-up compared to baseline, especially in step counts and MVPA. …”

General procedure for the synthesis of B. by Xueqin lu (22250795)

Patient Example. by James M. Friedman (22522150)

Juvenile demyelination impairs the maturation of PV interneurons in the PFC. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”

PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. by Sara Hijazi (21656615)

Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”

Predicting Dinitrogen Activation and Coupling with Carbon Dioxide and Other Small Molecules by Methyleneborane: A Combined DFT and Machine Learning Study by Feiying You (22119041)

“…N₂ coupling is examined as a concerted step, as CO₂ is a σ donor and a π acceptor. …”

Inhibition of foam cell formation. by Bruno Musetti (9527085)

Effect of the cannabis extracts on the accumulation of scavenger receptors. by Bruno Musetti (9527085)

Juvenile demyelination induces a loss of functional autapses. by Sara Hijazi (21656615)

“…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …”

AUT00201 (1 µM) can rescue AP width in cuprizone mice. by Sara Hijazi (21656615)

“…In the responsive cells from cuprizone mice (red) a significant increase in PV interneuron firing frequency at lower current steps (gray) was observed (<i>group x current two-way repeated measures: n = 8 cells from 4 mice: p = 0.05287; AUT00201 effect: F(1,60) = 5.050, *p = 0.0457. …”

Autapses play a crucial role in PV interneuron’s sustained firing at high frequencies. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0−650 pA current steps illustrating a significant increase in PV interneuron firing frequency at low-current steps in control cells without autapses (gray) compared to control cells with autapses (black). …”

Comparison between juvenile and adult demyelination. by Sara Hijazi (21656615)

“…Juvenile demyelination leads to impairment in PV interneuron maturation whereas adult demyelination induces a decrease in the excitability of PV interneurons. Summary data showing the averaged (± s.e.m) of the following intrinsic properties: (A) Resting membrane potential (RMP) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: *p < 0.05, **p < 0.01, ****p < 0.0001</i>), (B) Input resistance (IR) (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0024, post-hoc LSD test: *p < 0.05, **p < 0.01, ***p < 0.001</i>), (C) Sag (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0083, post-hoc LSD test: *p < 0.05, **p < 0.01</i>), (D) Rheobase (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, p = 0.1230, post-hoc LSD test: *p < 0.05</i>) and (E) Action potential (AP) threshold (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, *p = 0.0452, post-hoc LSD test: *p < 0.05</i>), (F) AP half-width (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, **p = 0.0058, post-hoc LSD test: **p < 0.01</i>), (G) Average action potential (AP) frequency in response to 0–650 pA current steps illustrating no significant change in S1 PV interneuron firing frequency following juvenile demyelination (<i>group x current two-way repeated measures: n = 36,30,19,24 cells from 9/8/8/6 mice per group: F(39,1,291) = 2.487, ****p < 0.0001</i>) and (H) Maximum firing frequency per group (<i>ANOVA: n = 36,30,19,24 cells from 9/8/8/6 mice per group, ****p < 0.0001, post-hoc LSD test: ***p < 0.001, ****p < 0.0001</i>). …”