Figure 3 from A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations by Shuaipeng Geng (20612220)

“…<p>Outcome of the two-step MCED approach in the case–control study. In the case–control cohort, the two-step MCED approach significantly improved specificity from 91.0% to 99.3%, whereas sensitivity decreased from 49.9% to 39.9%. …”

This is the data set that we used to reach the conclusions drawn in the manuscript with related metadata and methods. by Farayi Kaseke (19560197)

Genetic evidence linking gastroesophageal reflux disease to chronic kidney disease and kidney failure: a two-step Mendelian randomization study by Fanghong Zheng (8931326)

“…Interventions with these factors could significantly decrease the burden of CKD attributable to GERD.…”

Overexpression of TNFAIP9 alleviated the renal fibrosis caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 suppressed inflammation in mouse peritoneal macrophages caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 remitted the renal inflammation caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 inhibited the TGF-β-induced fibrosis in HK-2 cells. by Ying Chen (9697)

TNFAIP9 expression was increased in mice with chronic kidney disease (CKD) induced by 5/6 nephrectomy (Nx). by Ying Chen (9697)

Overexpression of TNFAIP9 counteracted the renal damage caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Overexpression of TNFAIP9 inhibited the TNF-α-induced inflammation in HK-2 cells. by Ying Chen (9697)

Additional within-case comparison information. by Ryan J. Treves (13527735)

“…While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

POTW sample summary. by Ryan J. Treves (13527735)

“…While the state’s introduction of $3,000 mandatory minimum penalties for certain Clean Water Act effluent and reporting violations by permitted wastewater facilities reflected a significant step-up in enforcement, the policy also allowed small communities with financial hardship to redirect penalties toward investments in compliance. …”

Characteristics of the participants. by Kensaku Sasayama (741571)

“…Overall physical activity levels decreased at follow-up compared to baseline. However, the contribution of commuting school activities to overall physical activity significantly increased at follow-up compared to baseline, especially in step counts and MVPA. …”

General procedure for the synthesis of B. by Xueqin lu (22250795)

Patient Example. by James M. Friedman (22522150)

Juvenile demyelination impairs the maturation of PV interneurons in the PFC. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in cuprizone-treated mice. …”

Predicting Dinitrogen Activation and Coupling with Carbon Dioxide and Other Small Molecules by Methyleneborane: A Combined DFT and Machine Learning Study by Feiying You (22119041)

“…The capture of carbon dioxide is extremely important due to the increasingly severe greenhouse effect, and the conversion of dinitrogen into high-value N–C compounds is of great significance. Here, we predict through density functional theory calculations that the coupling of dinitrogen with carbon dioxide by methyleneborane becomes favorable both thermodynamically and kinetically. …”

PV interneurons from Shiverer mice show many similarities with the ones from mice that underwent juvenile demyelination. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in Shiverer mice (<i>group x current two-way repeated measures: n = 25/25 cells from 9 mice per group: F(13,624) = 2.303, **p < 0.0056</i>). …”

Adult demyelination has no effect on PV interneuron’s firing rate or failures in autaptic responses. by Sara Hijazi (21656615)

Remyelination in adulthood leads to an incomplete restoration of PV interneuron properties. by Sara Hijazi (21656615)

“…Average action potential (AP) frequency in response to 0-650 pA current steps illustrating a significant decrease in PV interneuron firing frequency in remyelination (green) mice (<i>group x current two-way repeated measures: n = 25/19 cells from 8 mice per group: F(13,546) = 3.962, ***p < 0.001</i>). …”