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significant threat » significant effect (Expand Search), significant increase (Expand Search), significant decrease (Expand Search)
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75501
Table5_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.XLSX
Published 2022“…After NAC, the proportions of M1, γδT cells, and resting CD4 memory T cells were increased, while the proportions of natural killer cells and dendritic cells were decreased with downregulated immune-related genes. …”
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75502
DataSheet1_Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics a...
Published 2024“…<p>Background: Cardiovascular diseases (CVD) continue to threaten health worldwide, and account for a significant portion of deaths and illnesses. …”
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75503
MPK6 negatively regulates MYB46 function <i>in planta</i>.
Published 2021“…<p>(A) Promoter activities of MYB46 target genes were decreased by <i>CAMPK6</i> co-expression. …”
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75504
Data Sheet 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…</p>Methods<p>In this study, the chronic unpredictable mild stress (CUMS) method was used to establish a rat model of depression to investigate the ameliorative effects of HLTP on depression.…”
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75505
Table 1_Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban commun...
Published 2025“…Background<p>rs440446 (+ 113G/C), located in the intron of the APOE gene, has unclear effects on cognition, blood lipids, metabolic markers, and neural activity in older Chinese adults.</p>Methods<p>A total of 505 older adults from communities in Qingdao were enrolled and categorized into C-allele carriers (n = 451) and GG homozygotes (n = 54) based on the sequencing result. …”
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75506
Induction of ELF5 alters FOXA1 and ER binding to the genome.
Published 2020“…<p>Panel <b>A</b>, UpSet presentation of DiffBind output that identified statistically significant increases in FOXA1 or ER binding in response to induction of ELF5 with doxycycline (Dox). …”
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75507
Comparison of microwave ablation treatments in patients with renal secondary and primary hyperparathyroidism
Published 2020“…The volume of each gland was smaller, and the time of ablation for a single parathyroid was shorter in the SHPT group, although there were no significant differences compared with patients in the PHPT group. …”
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75508
An ecological approach to monitor geographic disparities in cancer outcomes
Published 2019“…Moreover, there is significant variation in the methods and constructs used to create area-level indices.…”
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75509
Data Sheet 1_Synchronized nutrition fertilizer improves soil microbial diversity and sugarcane yield through agrochemical and enzymatic regulation.docx
Published 2025“…In 2020, soil microbial diversity was enriched by SNFert through regulating microbial communities and functions. As a new kind of chemical fertilizer, SNF1 overcame the shortcomings of CF in reducing the soil microbial diversity, that was, there were no statistically differences in microbial alpha diversity indices between SNF1 and CK. …”
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75510
Table1_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.DOCX
Published 2022“…After NAC, the proportions of M1, γδT cells, and resting CD4 memory T cells were increased, while the proportions of natural killer cells and dendritic cells were decreased with downregulated immune-related genes. …”
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75511
Data_Sheet_1_New Insights Into Lignification via Network and Multi-Omics Analyses of Arogenate Dehydratase Knock-Out Mutants in Arabidopsis thaliana.zip
Published 2021“…While prior work helped explain lignin biosynthesis regulation at the transcriptional level, our data here provide support for a new hypothesis that there are additional post-transcriptional and translational level processes that need to be considered. …”
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75512
Identification of key genes involved in the recurrence of glioblastoma multiforme using weighted gene co-expression network analysis and differential expression analysis
Published 2021“…Three gene modules were correlated with recurrence and 2623 genes were clustered in these clinically significant modules. Among these, 13 genes – <i>EHF, TRPM1, FXYD4, CDH15, LHX5, TP73, FBN3, TLX1, C1QL4, COL2A, SEC61G, NEUROD4</i> and <i>GPR139</i> – were differentially expressed in recurrent GBM samples; low <i>LHX5</i> and <i>TLX1</i> expression predicted poor outcomes. …”
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75513
Table3_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.XLSX
Published 2022“…After NAC, the proportions of M1, γδT cells, and resting CD4 memory T cells were increased, while the proportions of natural killer cells and dendritic cells were decreased with downregulated immune-related genes. …”
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75514
Data_Sheet_1_Transcriptional differences between major Fusarium pathogens of maize, Fusarium verticillioides and Fusarium graminearum with different optimum growth temperatures.doc...
Published 2022“…The results showing different responses pattern of these pathways provides a foundation for further investigation of the molecular mechanisms underlying distinct thermal ecological niches of F. verticillioides and F. graminearum.…”
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75515
Data Sheet 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind...
Published 2025“…</p>Methods<p>In this study, the chronic unpredictable mild stress (CUMS) method was used to establish a rat model of depression to investigate the ameliorative effects of HLTP on depression.…”
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75516
Table 1_Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.docx
Published 2025“…Compared to the DSS group, the SA-Q-CS MPs treatment group showed significant improvements, with the Disease Activity Index (DAI) and histopathological scores reduced by more than 66.9%, pro-inflammatory factor levels decreased by 65%, antioxidant levels increased over sevenfold, and tight junction protein expression elevated by more than threefold. …”
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75517
Table 1_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…<p>Non-alcoholic steatohepatitis (NASH) is characterized by steatosis, inflammation, and hepatocyte damage. A Western-style diet characterized by excessive n-6 polyunsaturated fatty acid (n-6 PUFA) intake, which is metabolized to pro-inflammatory arachidonic acids (AAs), might contribute to the exacerbation of NASH. …”
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75518
Data Sheet 1_Enhancing tuber yield and nutraceutical quality of potato by supplementing sunlight with LED red-blue light.pdf
Published 2025“…This knowledge could be useful in controlled environment agriculture and indoor cultivation (i.e., vertical farming) as well as in space research on potato, as this crop is a candidate for plant-based regenerative systems for long-term missions.…”
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75519
Presentation_1_New Insights Into Lignification via Network and Multi-Omics Analyses of Arogenate Dehydratase Knock-Out Mutants in Arabidopsis thaliana.pdf
Published 2021“…While prior work helped explain lignin biosynthesis regulation at the transcriptional level, our data here provide support for a new hypothesis that there are additional post-transcriptional and translational level processes that need to be considered. …”
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75520
Image_3_Risk stratification based on DNA damage-repair-related signature reflects the microenvironmental feature, metabolic status and therapeutic response of breast cancer.tif
Published 2023“…Integrating public datasets and bioinformatics algorithms, we developed a robust prognostic signature based on 27 DRGs. …”