Molecular features influencing clinical outcome of advanced HER2-positive gastric cancer receiving trastuzumab plus chemotherapy by Yu Lei (266919)

“…Additionally, after treatment, TMB significantly increased in non-responders, while CIN significantly decreased in responders.…”

Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX by Mingming Zhao (760369)

“…Only three bile acid metabolites, taurodeoxycholic acid, taurochenodeoxycholic acid, and deoxycholic acid, were significantly different between the ANLF1 and ANLF2 groups, increasing at first and then decreasing with the aggravation of liver injury. …”

Data Sheet 1_Baicalein ameliorates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and regulating gut microbiota.docx by Weiguang Lv (8622405)

“…After baicalein treatment, the proinflammatory cytokines (TNF-α, IL-1β), and anti-inflammatory cytokine (IL-10) has decreased. Additionally, high-dose of baicalein strongly reversed oxidative stress alterations caused by DSS, as evidenced by Fe²⁺, MDA, ROS significantly depleted, and MPO, SOD, GSH significantly increased. …”

Image 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.jpeg by Na Wang (193263)

“…Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

Supplementary Figures_Fainshtein.pdf by Kfir Sharabi (21415808)

“…The acetylation state of PGC-1α significantly influences its coactivating potential, with increased acetylation—whether induced genetically or chemically—shown to suppress its gluconeogenic activity and lower hyperglycemia. …”

Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria... by Huaxiang Liu (322464)

“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”

Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Silencing Tnfaip6 significantly impaired osteogenic differentiation, as indicated by reduced alkaline phosphatase activity and downregulation of key osteogenic marker genes. …”

Image 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial.tif by Huaxiang Liu (322464)

“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Silencing Tnfaip6 significantly impaired osteogenic differentiation, as indicated by reduced alkaline phosphatase activity and downregulation of key osteogenic marker genes. …”

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Silencing Tnfaip6 significantly impaired osteogenic differentiation, as indicated by reduced alkaline phosphatase activity and downregulation of key osteogenic marker genes. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Silencing Tnfaip6 significantly impaired osteogenic differentiation, as indicated by reduced alkaline phosphatase activity and downregulation of key osteogenic marker genes. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Silencing Tnfaip6 significantly impaired osteogenic differentiation, as indicated by reduced alkaline phosphatase activity and downregulation of key osteogenic marker genes. …”

Table 1_Synergistic effects of multi-enzyme supplementation on nutrient digestion and absorption in the foregut and hindgut.docx by Fangyuan Chen (2147119)

“…Furthermore, during the fermentation of the enzymatic hydrolysis products, MCPC significantly increased the FRD₀ value of the enzymatic hydrolysis products from both the positive control (PC) and negative control 1 (NC1) diets (p < 0.05). …”

Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip by Quan Lin (5958)

“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”

Presentation 1_Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.pptx by Ryohei Yamamura (20386047)

“…Moreover, after steroid tapering, in non-relapsed patients, genes with increased expression were enriched in inflammatory pathways, represented by interferon signaling, while genes with decreased expression were enriched in pathways related to IL-10 and glucocorticoid receptors. …”

Prevalence of Vision Loss in North Africa and Middle East in 2020: Magnitude and Temporal Trends by Vision Loss Expert Group of the Global Burden of Disease Study (20987841)

“…</p> <p>Although the absolute numbers of people with blindness and MSVI have increased between 1990 and 2020 in NAME region, the overall prevalence and the age standardized prevalence in those aged 50+ years have decreased significantly for the same period.…”

Table 1_Effect of strip width in maize/peanut intercropping on water use efficiency.docx by Xianglong Sun (18834553)

“…However, compared to PS, water captured by intercropped peanut rows decreased by 20.6%, 13.2%, and 7.1%, respectively. …”

Supplementary Material for: Impact of Liraglutide 3.0 mg on Metabolic Dysfunction-Associated Steatotic Liver Disease in Individuals with Obesity: A Real-World Study by figshare admin karger (2628495)

“…Hepatic steatosis index (HSI) and non-alcoholic fatty liver disease (NAFLD) liver fat score also decreased significantly (HSI: 44.7 ± 6.2 to 42.2 ± 5.8 p<0.001; NAFLD liver fat score: 2.12 ± 2.90 to 0.43 ± 1.91, p<0.001). …”

DataSheet1_Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis.PDF by Hongmei Yu (584700)

“…</p>Results<p>After treatment with HKC, EB, and their combination for 4 weeks, the urinary albumin-to-creatinine ratios decreased significantly in the db/db mice with DN. …”

Table 1_Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia.docx by Tiantian Yu (5167427)

“…Correlation analysis revealed positive associations between CC group-decreased Lactobacillus abundance and CC group-decreased metabolites. …”