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significant trend » significant threat (Expand Search), significant threats (Expand Search), significant burden (Expand Search)
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12761
Table3_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studies.x...
Published 2024“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”
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12762
Data Sheet 2_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.zip
Published 2025“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”
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12763
Data Sheet 1_Cytokine-driven glycosphingolipid metabolism modulates endoplasmic reticulum calcium homeostasis in primary human renal mesangial cells.pdf
Published 2025“…The increase in cytosolic Ca<sup>2+</sup> was attributed to a decrease in endoplasmic reticulum (ER) Ca<sup>2+</sup> store capacity. …”
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12764
Image2_Constructing more comprehensive pollination networks: integrating diurnal and nocturnal pollen data with visitation in a subalpine wetland community.jpeg
Published 2024“…Consequently, nestedness decreased 0.8-fold, but mean plant connectivity went from 14.2 to 16.2.…”
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12765
Variation in defensive traits against herbivores of native and invasive populations of <i>Carpobrotus edulis</i>
Published 2025“…This release from natural enemies might decrease the investment in expensive defense mechanisms (i.e., digestibility reducers) against the attack of specialist enemies, whilst increasing the investment in defenses (i.e., cheap toxins) and tolerance against the attack of generalist herbivores, as exposed by the Shifting Defense Hypothesis (SDH). …”
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12766
Short-Ranged United-Atom Model for Efficient Simulations of Glycerol and Its Aqueous Mixtures
Published 2025“…While AA simulations are widely used, they overestimate the α-conformation and incur significant computational costs. Coarse-grained (CG) models provide an efficient alternative but have yet to accurately describe glycerol’s conformational distribution and thermodynamic behavior. …”
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12767
Data Sheet 1_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.pdf
Published 2025“…Additionally, we identified an increase in the ARGORNPROST-PWY pathway (L-arginine degradation, q = 0.003) and a decrease in the PWY-6478 pathway (GDP-D-glycero-α-D-manno-heptose biosynthesis, q = 0.015) in MSA patients compared with HCs.…”
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12768
Table 5_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx
Published 2025“…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …”
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12769
Image_3_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.tif
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”
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12770
Table 3_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx
Published 2025“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”
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12771
Datasheet2_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi...
Published 2024“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”
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12772
Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi...
Published 2024“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”
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12773
Video 2_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.avi
Published 2025“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”
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12774
Supplementary Material for: Association between blood flow measured within 30 days from AV access creation and thrombosis risk
Published 2025“…In dAVF, Qa showed a significant non-linear association with thrombosis risk, with nadir at Qa of 1289 ml/min and an exponential risk increase for Qa <800 ml/min. …”
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12775
Data Sheet 1_Characterization and immunoprotection of thioredoxin reductase TrxB knockout mutant of Salmonella Enteritidis.pdf
Published 2025“…We also observed a significant decrease in the expression of virulence-related genes in the trxB-knockout mutant. …”
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12776
Table 1_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.docx
Published 2025“…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …”
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12777
Image 5_The effect of COVID-19 and sex differences on natural killer cell cytotoxicity.tif
Published 2025“…To study the function of NK cells in patients hospitalized with COVID-19, peripheral blood was obtained from patients admitted to the medical (non-ICU) wards at a large tertiary hospital. We demonstrated a decrease in the mature cytotoxic subset of NK cells within the peripheral blood of patients hospitalized with COVID-19. …”
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12778
Data Sheet 1_The role of statins in dementia or Alzheimer’s disease incidence: a systematic review and meta-analysis of cohort studies.docx
Published 2025“…Similarly, an analysis of 19 studies comprising 1,237,341 participants demonstrated a 29% decrease in the risk of AD among statin users (HR: 0.71, 95% CI: 0.60–0.85). …”
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12779
Image1_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.tif
Published 2024“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”
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12780
Table 2_Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.xlsx
Published 2025“…</p>Results<p>There were significant differences in metabolic profiles among the UA, AMI and control groups. …”