Supplementary Material for: Does oXiris Matter? A Comparative Outcome Study in CRRT-Treated Septic ICU Patients by figshare admin karger (2628495)

“…Inflammatory markers (CRP, PCT) remained elevated in oXiris patients through day 5, while hemodynamic stabilization (lactate decline, norepinephrine reduction) was more pronounced. Platelet counts decreased in both groups without recovery. Conclusions: Our study demonstrated that patients with sepsis treated using the oXiris filter exhibited significantly higher ICU survival rates, despite higher mechanical ventilation duration and ICU length of stay. …”

Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif by Toru Miwa (8528715)

“…Despite similar metabolic trends in CBA mice, their slower aging profiles mitigated ARHL progression. …”

Reactive Organic Gases from Vehicle Evaporative Emissions: Rates, Compositions, and Temperature Effects by Jun Lu (36049)

“…The emission composition shifted significantly across high-, normal-, and low-emitting vehicles: traditional hydrocarbons decreased progressively, while carbonyls/ketones increased, attenuating hydroxyl radical reactivity (OHR) reduction. …”

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf by Juanjuan Zhang (432819)

“…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …”

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx by Juanzhao Cao (22651742)

“…Introduction<p>This study comprehensively investigated the magnitude and temporal trends of the global burden of opioid use disorder (OUD) from 1990 to 2021 and predicted the disease burden in the next 29 years.…”

Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

“…</p>Results<p>Fluorescence imaging revealed ISF transport along the linea alba, with tracers migrating linearly, a pattern abolished by surgical blockade. …”

Table 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.docx by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”

Presentation 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy coho... by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”

Image 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.pdf by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx by Monika Marko (7926311)

“…Education resulted in equalizing the level of correctness of inhalation, which was similarly high for each type of device. This means that after education, all inhalers have similar difficulty levels in performing the correct inhalation technique. …”

FSA inhibits MaAKT1 channels through <i>S</i>-glutathionylation. by Jun Zhang (48506)

“…Representative whole-cell current traces and summary of the preventive effect of GSH (2 mM) in the pipette on FSA-induced MaAKT1 inhibition (n = 3). Ns, not significant compared with the control group. Data in (<b>B</b>) to (<b>D</b>) are shown as means ± SE and compared using Student’s t-test (<b>C</b>) or paired Student’s t-test (<b>B</b> and <b>D</b>). …”

Data Sheet 1_Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021... by Jiaxin Hao (18837682)

“…Background<p>Breast cancer is one of the most prevalent tumors worldwide, significantly compromising the survival and quality of life of patients. …”

Data Sheet 1_Spatial and temporal variability in blue carbon accumulation in the largest salt marsh in British Columbia, Canada.docx by Karen E. Kohfeld (11936879)

“…These contrasting trends suggest dynamism in marsh development, likely driven by environmental factors and human influence. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. …”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…</p>Methods<p>In this study, we evaluated the synergism of tigecycline combining with other antibiotics as a means of overcoming the tet(X)-mediated resistance in Acinetobacter spp. …”

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. by Aïssatou Aïcha Sow (20371233)

“…<i>N</i> = 3). Data are shown as means ± SEM. **** P ≤ 0.0001; ns = not significant; one-way ANOVA. …”

Behavior is best fit by models with independent attributes. by Aster Q. Perkins (22008260)

“…Bars show across-session means, circles show values from individual sessions. …”

Image 1_Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation.tif by Jingyi Hou (698975)

“…</p>Results<p>MitoDEGs in the MI group were significantly enriched in pathways related to mitochondrial transport and gene expression. …”

Table 3_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.docx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”