Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”

Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese by Abdelkrim Khadir (437074)

“…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …”

Sitagliptin/Simvastatin by Ramadan, Wijdan H.

“…Further, trials have shown a beneficial effect of using statins in patients with diabetes mellitus with regard to decreasing cardiovascular risk, regardless of baseline lipid levels or the presence of a cardiac disease. …”
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Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome by Fayaz Ahmad Mir (11828354)

“…We measured 1069 serum metabolites and correlated them to clinical features. Results: A total of 83 metabolites, mostly lipids, were significantly different (p < 0.05) between the two groups. …”

Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …”
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How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly by Ramada R. Khasawneh (6837734)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Irish Journal of Medical Science (1971 -)<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11845-024-03813-3" target="_blank">https://dx.doi.org/10.1007/s11845-024-03813-3</a></p>…”

Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems by Shazia Bibi (16500318)

“…Moreover, the germination rate of A. tortilis was not affected; however, the seed germination of P. cineraria was significantly affected at concentrations of 6 and 8 mg mL−1. …”

Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden by Farra, Anna

“…Cotrimoxazole resistance has also been increasing significantly in most hospitals, in spite of decreasing sales of cotrimoxazole and trimethoprim. …”
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Amira Othman (380131)

“…Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …”

Corporate Governance and the diversification discount by Boumosleh, Anwar

“…However, we find that the sensitivity of the diversification discount to CEO power decreases significantly after the implementation of the Sarbanes-Oxley Act, which implies that the restrictions and regulations passed by the act enhance corporate governance and limit the misallocation of resources and the diversification discount respectively.…”
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The anti-cancer activity of 2 himachalene-6-OL extracted from daucus carota SSP. carota. (c2014) by Najm, Paul I.

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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”

Predicting stability of classes in an object-oriented system by Azar, D.

“…However, in almost all cases, these models were not efficient when used to predict the quality characteristics (stability or other) of new unseen software as their prediction accuracy decreases significantly. In this paper, we present a heuristic approach that relies on the adaptation and recombination of already built predictive models to new unseen software.The predictive models are all rule-based models and the approach is tested on the stability of classes in an object-oriented software system. …”
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Fraud by Jizi, Mohammad

“…Because of the recent collapse of several major companies, investors' confidence in audited financial statements has decreased significantly. Fraud has been a major topic among many scholars and stakeholders due to its importance and impact on financial statements and economies at large. …”
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Dynamic Performance Investigation of Solar‐Driven Vapor Absorption Cooling System for Urban Areas by Laveet Kumar (11460088)

“…For both flat plate and ETCs, increasing the collector area increased the SF and primary energy savings while increasing the capacity of thermal storage decreased the SF and primary energy savings. For varying thermal storage volumes, the SF varies very little when using flat plate collector but significantly when using ETC. …”

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy by Olfa Khalifa (10914452)

“…Analysis of the Oil Red O staining showed that Ex-4 significantly reduces steatosis. This reduction was confirmed by FTIR analysis, as the phospholipid band (C=O) at 1740 cm−1 in Ex-4 treated cells is significantly decreased compared to steatotic cells. …”

Natural resource dependence and war nexus: new insights by Al Shami, Farah

“…Using a panel probit model, we find that natural resources rents, military expenditures, and the presence of a common law tradition significantly increase the probability of war occurrence. …”
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Nonlinear effects in locally resonant nanostrip phononic metasurface at GHz frequencies by Feng Gao (3548)

“…The power-dependent coupling of nanostrips in the NPM resonator demonstrates a reliable method for the realization of nonlinearity in phononic metasurfaces, which would significantly enrich the mechanisms for the manipulation of surface acoustic waves at high frequencies.…”

The distribution of toxic sources in Louisiana by Djoundourian, Salpie Sarkis

“…The results reveal that income levels in communities that host toxic sources are consistently and significantly lower than the state averages. A distance gradient analysis indicates that as distance from the nearest toxic source increases, the mean percentage of blacks in the community decreases and the mean percentage of whites increases. …”
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