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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
منشور في 2023"…This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …"
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
منشور في 2025"…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …"
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The value for money factors and their interrelationships for smart city public–private partnerships projects
منشور في 2022"…Originality/value In addition to the theoretical and methodological contributions, this study produced a usable and readily adaptable list and clusters of value for money factors for the implementation of PPP in smart infrastructure projects.…"
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Exploring the value of project management: Linking Project Management Performance and Project Success
منشور في 2014"…The literature on Project Management (PM) shows that, in spite of advancement in PM processes, tools and systems, project success has not significantly improved. This problem raises questions about the value and effectiveness of PM and PM systems. …"
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Decision Support Model for Optimal Design of Wind Technologies Based Techno–Economic Approach
منشور في 2021"…<p dir="ltr">This paper aims to propose a practical decision support model for the optimal design of future wind turbines based on available wind potential on the site of interest. …"
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Exploring differences in work values among multigenerational workforce: Leadership approaches in selected higher educational institutions in the UAE
منشور في 2017"…The study is based on a mixed-method approach (a work value inventory-based questionnaire and semi-structured interviews with managers employed by the abovementioned universities), and attempts to better understand values of Millennials, Baby Boomers and Generation X-ers employed within the UAE universities. …"
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The role of blockchain in enabling inter organisational supply chain alignment for value co-creation in the construction industry
منشور في 2023"…A conceptual model is developed based on the service-dominant logic theory that explores the impact of blockchain on supply chain alignment and co-created value outcomes within the Business-to- Business (B2B) construction context. …"
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The relationship between intellectual capital information and firms’ market value: a study from an emerging economy
منشور في 2019"…</p><h3>Findings</h3><p dir="ltr">The study found that there is a significant relationship between IC information and firm market value. …"
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Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients
منشور في 2018"…The data was considered to be statistically significant when FDR-adjusted P value < 0.05.</p><h3>Results</h3><p dir="ltr">High mRNA expression of around 80% of ligands for NK activating and inhibitory receptors associated with better RFS, which correlated with longer OS for only about half of the NK-activating ligands but for most NK-inhibitory ligands. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …"
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Hedging Strategies Using Financial Derivatives in Different Industries
منشور في 2025احصل على النص الكامل
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…"