Muscles influence motoneuron at NMJ during the critical period, but motoneuron do not affect GluR composition in muscles. by Daniel Sobrido-Cameán (5049743)

“…<p><b>(A)</b> Heat stress experienced during the embryonic critical period (32°C vs. 25°C control) leads to decreased postsynaptic GluRIIA. Simultaneous genetic manipulation of aCC motoneuron during embryonic stages does not affect GluRIIA in muscles. …”

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model by Gao Xi (22574101)

“…Intra-articular delivery of FGF18 in destabilized medial meniscus (DMM)-induced PTOA mice significantly reduced cartilage erosion and markedly decreased synovial thickening compared to saline-treated controls, with improved cartilage matrix integrity. …”

Differential neural dynamics in the GNP model incorporating electrodiffusion and ion concentration changes. by Zichao Liu (4591993)

“…(f) The harmonic means of intramembrane potassium and chloride concentrations increase, whereas for sodium, it decreases during neural activity. …”

Quantification of faecal glucocorticoid metabolites as a measure of stress in the rock hyrax (Procavia capensis) living in an urban green space by Scheun, Juan (8229483)

“…Animal FID did not differ significantly between seasons but they did differ significantly between sections, and decreased in accordance with fGCM concentrations. …”

DMSO induces a reduction in somite’s size. by Geyse Gomes (22075629)

“…Somites’ thickness significantly decreases after treatment with 2%, 3% and 4% DMSO (D). ns = non-significant. …”

Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx by Julio Cesar Santos-Pelaez (22674113)

“…The combination of 100 kg K₂O ha⁻¹ and 50 mg L⁻¹ GA₃ significantly improved fruit performance, with fruit weight (369.5 g), yield (12 t ha⁻¹), volume (322 cm³), and soluble solids (22.8°Brix), while acidity decreased (pH 4.87 vs. 4.55 in the control). …”

Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf by Li Yang (6520)

“…However, the number of DALYs attributed to population ageing among people aged 65 and older has been increasing by 10.45 million. Chronic obstructive pulmonary disease, stroke, and ischemic heart disease are most significantly affected by the aging trend. …”

Rheological investigations of fresh fiber-reinforced cementitious composites using hydrophobic/hydrophilic UHMWPE fibers for 3D concrete printing evaluation by Yan Sun (22436)

“…Hydrophilic fibers significantly enhanced microstructural rigidity, followed by hydrophobic fibers and nanoclay, evidenced through an increase of storage modulus by 115.29%, 59.37%, and 49.49%, respectively. …”

Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx by Dan-Ni Yang (17642947)

“…Subgroup analyses with both cohorts revealed the decreased AUC in older patients. The resampling method revealed decreased AUC with the advancement of age.…”

Data Sheet 2_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.xlsx by Li-Yan Zhang (5091608)

“…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …”

Data Sheet 1_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.docx by Li-Yan Zhang (5091608)

“…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …”

GABA and glutamate are required for light avoidance. by Kenichi Nakayama (2354653)

“…<i>Ppa-unc-25</i> and <i>Ppa-eat-4</i> mutants exhibit decreased light avoidance. One-way ANOVA Dunnett’s multiple comparison tests, compared with wild type. n.s = not significant, *<i>P</i> < 0.05, ****<i>P</i> < 0.0001.…”

DataSheet1_The Impact of Unmet Healthcare Needs on the Perceived Health Status of Older Europeans During COVID-19.pdf by Šime Smolić (15918211)

“…</p>Results<p>Findings indicate that unmet healthcare needs decreased throughout the pandemic but significantly contributed to the worsening of SRH among older adults. …”

Table 1_Epicatechin gallate and its analogues interact with sortase A and β-lactamase to suppress Staphylococcus aureus virulence.docx by Fei Teng (201085)

“…The ability of β-lactam antibiotics to combat S. aureus infections is limited by the presence of β-lactamases in this pathogen. In this study, we determined that epicatechin gallate (ECG) and its analogues inhibited the transpeptidase activity of sortase A by interacting with it directly, and the biofilm formation and adhesion abilities of the bacterium decreased after treatment with ECG and its analogues. …”

Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors by Xiaorui Han (1401655)

“…The Oil Red O staining experiment showed that <b>26e</b> decreased the lipid droplets in a dose-dependent manner. …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

Data Sheet 1_Comparison between 75-g and 100-g oral glucose tolerance tests using international association of diabetes and pregnancy study group one-step diagnostic threshold to d... by Li-Li Zhou (1710085)

“…However, from fasting to 2h, the 100g group showed a steeper rise than the 75g group [Difference in slope (95% CI):0.412 (0.244 to 0.580), p<0.05], and a slower decline between 1-2h [Difference in slope (95% CI):0.047 (0.010 to 0.084), p<0.05].Glucose-adjusted continuous analysis showed that blood glucose levels were mostly associated with adverse outcomes, with the strength of association gradually decreasing from fasting to 1h and 2h. Both groups exhibited similar trends, no significant differences in the risks of adverse outcomes (expressed as ORs) were observed between the 75g and 100g OGTT groups (all p > 0.05).…”

Enhancement of mechanical and thermal properties of porous alkaline cements using silica and alumina nanoparticles by Nuno Cristelo (20594563)

“…Al nanoparticles did not enhance mechanical performance, but led to density reduction, resulting in decreased strength. Thermal conductivity showed no significant variations due to nanoparticles, with all formulations classified as T2 thermal mortars. …”

Data Sheet 1_Changes in cortical brain activity after active break in preschoolers: MOVI-HIIT study.pdf by María Valdivieso-González (22225891)

“…</p>Results<p>EEG data revealing significant increases in Theta, Alpha1, and Alpha2 bands, suggesting enhanced relaxation, attentiveness, and readiness to learn. …”