Regional Characteristics in Ultradeep MXene Slit Nanopores: Insights from Molecular Dynamics Simulation by Kaiqing Sun (18715965)

“…As the interlayer spacing varies, the ion distribution in the electrode pores exhibits regional characteristics: in the ordered region near the bulk region, a stable electrical double-layer (EDL) structure is maintained, whereas in the deeper mixed region, persistent co-ion presence and significant disorder are observed. Dominated by the mixed region, the total energy variation of the electrode decreases as the interlayer spacing decreases, with energy changes of 8526.52, 7443.52, and 6640.99 kJ·mol^–1 at interlayer spacings of 1.2, 1.0, and 0.8 nm, respectively, representing reductions of approximately 12.7 and 22.1% compared to 1.2 nm. …”

Actin-Targeted Magnetic Nanomotors Mechanically Modulate the Tumor Mechanical Microenvironment for Cancer Treatment by Xing Fan (88299)

“…Cancer-associated fibroblasts (CAFs) and tumor cells, which internalize ∼69.3% of ABP-MNs, are significantly tuned under MF with signs of a 7-fold decrease in tumor matrix stiffness, increased immune cell infiltration, and 95.8% tumor growth inhibition. …”

Data for Fig 1. by Rachael M. Giersch (22331947)

“…We also observe a significant decrease in survival in animals that progress to >10% cancer in their hemolymph, while we see no effect on survival in clams with BTN that are long-term non-progressors. …”

Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. by Richard Junior Zapata Dongo (17912565)

Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. by Richard Junior Zapata Dongo (17912565)

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. by Richard Junior Zapata Dongo (17912565)

Anecdotal case of regression in a clam with naturally acquired BTN. by Rachael M. Giersch (22331947)

Negative (Prednisone) and basal (ATP) control compounds binding to ALK protein. by Richard Junior Zapata Dongo (17912565)

S1 Data - by Richard Junior Zapata Dongo (17912565)

“…This interaction was further supported by a significant decrease of ALK phosphorylation in single and combination treatment with 300nM ABT-199. …”

RNA targets of Mod identified by RiP-Seq. by Amalia S. Parra (4173004)

“…Mod is expressed in larval brains and its loss leads to a significant decrease in the number of central brain NBs. …”

ALKG1202R –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKC1156Y –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALKL1196M –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALK^wt–ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. by Richard Junior Zapata Dongo (17912565)

Changepoint analysis in comparison of MarBTN-specific eDNA and cancer in hemolymph. by Rachael M. Giersch (22331947)

Multiple distinct outcomes observed in soft-shell clams (<i>Mya arenaria</i>) after natural infection with MarBTN. by Rachael M. Giersch (22331947)

Modeling the relationship between cancer level in hemolymph and MarBTN in tank eDNA. by Rachael M. Giersch (22331947)

Advancing Circular Bioeconomy through a Systems-Level Assessment of Food Waste and Industrial Sludge Codigestion by Md. Nizam Uddin (21632518)

“…Simultaneously, pulp and paper mills produce significant amounts of recalcitrant organic waste that is difficult to decompose due to its high lignocellulosic content. …”

MarBTN-specific eDNA detection in each clam that was followed for MarBTN in hemolymph and eDNA. by Rachael M. Giersch (22331947)