Search alternatives:
significantly predicted » significantly reduced (Expand Search), significantly reduce (Expand Search), significant predictor (Expand Search)
predicted decrease » predicted secreted (Expand Search), reported decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
significantly predicted » significantly reduced (Expand Search), significantly reduce (Expand Search), significant predictor (Expand Search)
predicted decrease » predicted secreted (Expand Search), reported decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf
Published 2025“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”