Data Sheet 1_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xls by Wenyong Liao (21669332)

“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”

Association between the difference in estimated GFR based on cystatin C versus creatinine in coronary artery diseases by Zechen Liu (9200014)

“…When eGFR_diff was treated as a continuous variable, a statistically significant trend toward a lower risk of CAD as eGFR_diff increased (HR 0.982, 95% CI 0.981-0.982). …”

Changes in dorsal-ventral patterning of CA1 in COUP-TFI mutant hippocampus. by Ching-San Tseng (6252566)

“…The Dcn/Wfs1 ratio was significantly decreased in the cKO and increased in the cTG. …”

Table 1_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.xlsx by Qinghai Ren (20686166)

“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”

Data Sheet 1_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.pdf by Qinghai Ren (20686166)

“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”

Table 2_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.xlsx by Qinghai Ren (20686166)

“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”

Data Sheet 1_OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the fe... by Huiyu Xu (12255545)

“…AMH sampling on different cycle days showed only modest effects from minor fluctuations; only substantial AMH decreases significantly affected prediction accuracy. …”

Image 4_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Supplementary file 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.docx by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image 1_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Table 1_Shengxue Busui Decoction activates the PI3K/Akt and VEGF pathways, enhancing vascular function and inhibiting osteocyte apoptosis to combat steroid-induced femoral head nec... by Manting Liu (11207258)

“…In vivo, SBD intervention significantly reduced bone structural damage and apoptosis, decreasing the rate of empty bone lacunae. …”

Image 2_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Image 3_Cornuside mitigates acute lung injury through suppression of NLRP3 inflammasome-mediated pyroptosis and activation of the Keap1-Nrf2 antioxidant response.tif by Tong Luo (458639)

“…Introduction<p>Acute lung injury (ALI) is a life-threatening respiratory disorder characterized by excessive inflammation and oxidative stress, with no specific pharmacological therapy currently available. …”

Table_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... by Mingzheng Duan (11630632)

“…Background<p>Tian-ma (Gastrodia elata) is a traditional medicinal herb found in China. It is used in healthy food and to treat various diseases, therefore cultivated extensively in southwest China. …”

Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... by Mingzheng Duan (11630632)

“…Background<p>Tian-ma (Gastrodia elata) is a traditional medicinal herb found in China. It is used in healthy food and to treat various diseases, therefore cultivated extensively in southwest China. …”

RipU^K60 impacts actin cytoskeleton organization at 48 hours post infiltration. by Rachel Hiles (20477573)

“…(G,H) RipU^K60 significantly increased actin filament density (G), and decreased actin bundling (H) compared to controls at 48 hpi. …”

Data Sheet 1_Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway.csv by Jiejie Hu (6190622)

“…Protein–protein interaction (PPI) analysis combined with molecular complex detection (MCODE) identified six hub genes, namely, Ddit3, Atf3, Sesn2, Trib3, Ppp1r15a, and Gadd45a. Spearman’s correlation analysis revealed a significant correlation between the hub genes and ferroptosis-related DEGs. …”

Table_1_Hyperthyroidism, hypothyroidism, thyroid stimulating hormone, and dementia risk: results from the NHANES 2011–2012 and Mendelian randomization analysis.DOCX by Xixi Sheng (19932165)

“…</p>Conclusion<p>This study provides evidence of a nonlinear relationship between TSH and FT4 concentrations and cognitive function, with hyperthyroidism decreasing the risk of dementia and VaD, hypothyroidism increasing the risk of dementia and VaD, and elevated serum TSH concentrations increasing the risk of AD. …”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”

miR-155 directly targets the 3′UTR of TRAF3 and STAT1. by Xinyue Zhang (271120)

“…<p><b>(A)</b> The predicted target sites of miR-155 in TRAF3 and STAT1 3′UTRs, as well as the mutant forms with the potential miR-155 binding sites mutated. …”