Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Minimalist Natural ORPphilin Macarangin B Delineates OSBP Biological Function by Gwenaëlle Jézéquel (4488268)

“…Importantly, both enantiomers showed significantly decreased cytotoxicity compared to other ORPphilins, suggesting OSBP is not the primary target in ORPphilin-induced cell death. …”

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf by Alex Ramos (16267028)

“…Background<p>Preeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. …”

Data Sheet 1_Global burden of Type 2 Diabetes Mellitus attributable to dietary risks in elderly adults: insights from the Global Burden of Disease study 2021.docx by Yiting Tang (2295307)

“…Background<p>Type 2 Diabetes Mellitus (T2DM) poses a significant global health challenge, particularly among elderly adults. …”

Image 3_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…</p>Conclusion<p>The analysis indicates that while the global burden of NSNIs has decreased, the situation remains serious in Africa and Southeast Asia, with a continuing rise in the burden of NSNIs in the Eastern Mediterranean and Western Pacific regions in recent years. …”

Image 1_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…</p>Conclusion<p>The analysis indicates that while the global burden of NSNIs has decreased, the situation remains serious in Africa and Southeast Asia, with a continuing rise in the burden of NSNIs in the Eastern Mediterranean and Western Pacific regions in recent years. …”

Table 1_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.docx by Caini Mu (20997938)

“…</p>Conclusion<p>The analysis indicates that while the global burden of NSNIs has decreased, the situation remains serious in Africa and Southeast Asia, with a continuing rise in the burden of NSNIs in the Eastern Mediterranean and Western Pacific regions in recent years. …”

Image 4_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…</p>Conclusion<p>The analysis indicates that while the global burden of NSNIs has decreased, the situation remains serious in Africa and Southeast Asia, with a continuing rise in the burden of NSNIs in the Eastern Mediterranean and Western Pacific regions in recent years. …”

Image 2_Analysis of the global burden and key risk factors of neonatal sepsis and other neonatal infections in 204 countries and territories, 1990–2021.jpeg by Caini Mu (20997938)

“…</p>Conclusion<p>The analysis indicates that while the global burden of NSNIs has decreased, the situation remains serious in Africa and Southeast Asia, with a continuing rise in the burden of NSNIs in the Eastern Mediterranean and Western Pacific regions in recent years. …”

Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX by Pupu Yan (19710400)

“…Moreover, baicalin significantly enhanced the operational taxonomic unit (OTU) count in A. hydrophila-infected yellow catfish (P < 0.05), restoring the abundance of Barnesiellaceae, Enterobacteriaceae, Plesiomonas, and UBA1819 (P < 0.05).…”

Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx by Jiali Liu (327739)

“…Mechanistic investigations revealed that KA modulated fatty acid metabolism, retinol metabolism, and arachidonic acid metabolism by regulating the expression of key metabolic enzyme genes such as SCD, SCD2, FADS2, and CYP4A8, and significantly influenced the activity of the PPAR signaling pathway. …”

Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX by Pupu Yan (19710400)

“…Moreover, baicalin significantly enhanced the operational taxonomic unit (OTU) count in A. hydrophila-infected yellow catfish (P < 0.05), restoring the abundance of Barnesiellaceae, Enterobacteriaceae, Plesiomonas, and UBA1819 (P < 0.05).…”

Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Table_1_Effect of progesterone concentration on hCG trigger day on clinical outcomes after high-quality single blastocyst transfer in GnRH antagonist cycles.docx by Nan Jia (118883)

“…And the pregnancy rate decreased by 25% (95% CI: 0.51, 1.09) for frozen cycles, although there was no statistically significant (p = 0.1273). …”

Table_1_Effect of progesterone concentration on hCG trigger day on clinical outcomes after high-quality single blastocyst transfer in GnRH antagonist cycles.docx by Nan Jia (118883)

“…And the pregnancy rate decreased by 25% (95% CI: 0.51, 1.09) for frozen cycles, although there was no statistically significant (p = 0.1273). …”

Image 7_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…The gut microbiota of the HC group was categorized into enterotype Bacteroides (ET-B) and enterotype Prevotella (ET-P), whereas that of the PWH group exhibited ET-B, ET-P and enterotype Enterobacter (ET-E). ET-E was a unique enterotype in the PWH group, in which the abundance of Enterobacter was significantly increased. …”

Image 3_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…The gut microbiota of the HC group was categorized into enterotype Bacteroides (ET-B) and enterotype Prevotella (ET-P), whereas that of the PWH group exhibited ET-B, ET-P and enterotype Enterobacter (ET-E). ET-E was a unique enterotype in the PWH group, in which the abundance of Enterobacter was significantly increased. …”

Table 1_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.xlsx by Jiali Chen (5696)

“…The gut microbiota of the HC group was categorized into enterotype Bacteroides (ET-B) and enterotype Prevotella (ET-P), whereas that of the PWH group exhibited ET-B, ET-P and enterotype Enterobacter (ET-E). ET-E was a unique enterotype in the PWH group, in which the abundance of Enterobacter was significantly increased. …”