Data Sheet 1_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Data Sheet 2_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Table 1_Telestroke management during the Hajj seasons 2023–2024: insights from SEHA Virtual Hospital in KSA.xlsx by Ghadah Sulaiman Alsaleh (22611695)

“…Male patients rose from 57% in 2023 to 62% in 2024. Diagnoses showed significant variation: ischemic strokes increased from 46% in 2023 to 73% in 2024, while hemorrhagic strokes and other miscellaneous conditions decreased, and TIAs showed a slight increase. …”

Table 1_Burden of non-CO poisoning in 204 countries and territories, 1990–2021: results from the global burden of disease study 2021.docx by Rong Lei (4006232)

“…Background<p>Non-carbon monoxide (non-CO) poisoning remains a significant global public health issue, contributing to considerable morbidity and mortality. …”

Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx by Yihan Sun (3432287)

“…Background<p>Traumatic brain injury (TBI) represents a major global health challenge. Several clinical studies have suggested that Xuebijing (XBJ)—a patented Chinese botanical drug preparation may confer neuroprotective and anti-inflammatory benefits in TBI. …”

Data_Sheet_1_Compound effects of biochar application and irrigation on soil water and temperature transport.docx by Fuchang Jiang (19966587)

“…<p>The issue of soil salinization poses a significant barrier to sustainable agricultural development, particularly in arid and semi-arid regions. …”

Synergy is not captured by low-dimensional manifolds. by Thomas F. Varley (8446899)

“…<b>Top right:</b> The same pattern can be seen in synergy-dominated triads as well: a more strongly negative value is associated with decreasing variance explained by the first principal components. …”

Data Sheet 1_Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling.docx by Lanlan Sun (1798921)

“…Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. …”

The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation. by Cheng Zhong (573294)

“…<p>(A) The expression of CHRM2 was significantly reduced in cells knocked down with Si-CHRM2. …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Image 2_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

Image 1_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif by Xinxiao Gao (21717197)

“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”

Table 4_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Supplementary file 1_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Table 2_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Table 1_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Table 3_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Table 7_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period-cohort analy... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Supplementary file 2_Global, regional, and national temporal trends in prevalence, deaths and disability-adjusted life years for chronic pulmonary disease, 1990–2021: an age-period... by Wubing Cao (20821589)

“…Background<p>Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality globally, with significant disparities in disease burden across countries and socioeconomic regions. …”

Data Sheet 1_N-acetylcysteine reduces prefrontal reactivity to cocaine cues in individuals with cocaine use disorder.pdf by Etna J. E. Engeli (20793524)

“…Cue reactivity and subsequent craving significantly elevate the risk of substance use, creating a pressing need for treatments that can help alleviate cravings. …”