بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
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21161
Model framework.
منشور في 2024"…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …"
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21162
Protocol for our RNA-seq.
منشور في 2025"…GO enrichment was conducted using the Wormbase Gene Set Enrichment Analysis [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref046" target="_blank">46</a>,<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003144#pbio.3003144.ref047" target="_blank">47</a>]. …"
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21163
Essential model parameters.
منشور في 2024"…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …"
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21164
Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg
منشور في 2024"…Furthermore, DEX treatment reduced the expression levels of a GABA-synthesizing enzyme (GAD67), Reelin, calcium-binding proteins (parvalbumin and calretinin) and neuropeptides co-expressed in GABAergic neurons (somatostatin, neuropeptide Y and vasoactive intestinal peptide) in the PFC were reduced after 21 days of DEX treatment; these reductions were accompanied by decreases in brain size and cerebral cortex thickness.…"
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21165
Data Sheet 1_Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo).zip
منشور في 2025"…Introduction<p>The lotus (Nelumbo Adans.) is a versatile plant that integrates ornamental beauty, culinary applications, medicinal benefits, ecological significance, and cultural symbolism. …"
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21166
The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands.
منشور في 2025"…(E-G) were performed with replicates (n = 6; 3 SjD and 3 control) of our treatment conditions on the right with a representative western on the left; (E) pJAK1 proportion increased in a dose-dependent manner with increasing ruxolitnib; (F) pJAK2 proportion increased as ruxolitinib dose increased; (G) pSTAT1 decreased in a dose response relationship with increasing ruxolitinib. …"
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21167
Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf
منشور في 2024"…Agricultural land use was associated with decreased mycobiota alpha diversity and distinct fungal communities were observed at agricultural drainage ditch and mixed-land use sites compared to a forested site that had minimal anthropogenic activities in catchment. …"
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21168
Data Sheet 1_Metabolic adaptation to acute metabolic stress via PFKFB3 upregulation in rodent beta cells.doc
منشور في 2025"…Introduction<p>Pancreatic beta cells undergo metabolic remodeling in response to metabolic overload, but the functional significance of this remains unclear. 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3) is a glycolytic regulator that may play a role in beta cell adaptation under acute metabolic stress. …"
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21169
Effect of hypoxia on hepatocyte injury in NAFLD model mice.
منشور في 2025"…<p>(A) Analysis of mitochondrial membrane potential in hepatocytes in vivo. …"
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21170
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
منشور في 2025"…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …"
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21171
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …"
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21172
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …"
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21173
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…Background<p>The development of prostate cancer (PCa) remains a major health threat for men worldwide. Calcium/Calmodulin signaling pathway has been implicated to the initiation and progression of diverse human cancers. …"
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21174
Supplementary file 1_Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determinat...
منشور في 2025"…Compared to age-matched controls, proximal tibial BMAT tended to increase in CKD mice by 3 weeks’ induction and this reached statistical significance after 5-weeks where there was a negative correlation between regulated BMAT accumulation and trabecular bone loss. …"
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21175
Table1_The association of physical activity with kidney function risk among adults with long working hours.docx
منشور في 2024"…Introduction<p>Long working hours are likely associated with the decreased of kidney function, while physical activity (PA) was linked to improvements in kidney function. …"
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21176
Transcriptomic analysis of AMPK and HZL-1 mutants reveals widespread gene expression differences predominantly in the germ line.
منشور في 2025"…<p><b>A)</b> and <b>B)</b> Bubble plots depicting most enriched GO terms in <i><i>daf-2</i></i>, <i><i>daf-2, aak(0)</i>,</i> and <i><i>aak(0); hzl-1</i></i> transcriptomes, ranked by significance based on p-value. …"
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21177
H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment.
منشور في 2025"…<b>(B)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within SEACR-defined consensus peak regions. The significance threshold was a false-discovery rate <0.05, as defined by DiffBind [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref065" target="_blank">65</a>] (n = 4). …"
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21178
Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
منشور في 2025"…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …"
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21179
Table 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.docx
منشور في 2025"…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …"
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21180
Image 4_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
منشور في 2025"…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …"