Data Sheet 1_Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.zip by Junxian Hu (8158044)

“…In this study, we observed that under low hydrostatic pressure, TRPV4 activation and subsequent calcium influx led to an increase in CRT synthesis and a significant rise in its cytosolic expression. …”

List of abbreviations used in this paper. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

Image 1_Integrated microbiome and metabolomics analysis reveals the alleviating effect of Pediococcus acidilactici on colitis.pdf by Lulu Wu (7508612)

“…Microbiome analysis showed that colitis could cause a significant decrease in the gut microbial diversity and abundance, but Pediococcus acidilactici administration could restore the microbial index to the control level. …”

Estimation of the CO and CBF. by Liuchuang Wei (19273099)

“…Computational results revealed that hypovolemia reduces cerebral blood flow by approximately 100 mL/min due to a 30% decrease in blood volume, while vascular dysfunction—marked by a 50–100% increase in arterial stiffness—further diminishes cardiac output and cerebral perfusion. …”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…All patients achieved stable disease; however, a significant reduction in bone marrow blast percentage after one to two cycles of treatment was observed in two patients, which correlated with a decrease in FLT3-ITD allelic ratio and variant allele frequency of co-occurring mutations (e.g., NPM1 and DNMT3A). …”

Table 1_Modulation of the gut-bone axis: Lacticaseibacillus paracasei LC86 improves bone health via anti-inflammatory metabolic pathways in zebrafish models of osteoporosis and car... by Yao Dong (3308124)

“…Gut microbiota analysis demonstrated an increase in beneficial bacteria and a decrease in pathogenic genera.</p>Conclusions<p>LC86 significantly improved bone health, cartilage structure, and gut microbiota composition in a Dexamethasone-induced zebrafish model, supporting its potential as a therapeutic strategy for osteoporosis and cartilage injury via modulation of the gut-bone axis.…”

Data Sheet 1_Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia.pdf by Xiuzhang Xu (22363618)

“…Furthermore, the administration of anti-MHC-I antibodies to mice led to a significant decrease in the platelet count within 24 h. …”

Harmonisation phase total power analysed locally by the partners. by Tim P. Ahuis (19964467)

“…<p>Tukey boxplots and individual data points for the log₁₀ total power values per genotype group and every participating laboratory during phase 2 data collections. Lab 2 and Lab 3 found a significant decrease in total power in Tg4510 mice compared to WT controls (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0309521#pone.0309521.s006" target="_blank">S6 Table</a>). …”

VCC-induced pro-inflammatory response generation in BMDMs is dependent on TLR2, TLR4 as well as TLR1. by Shraddha Gandhi (21001590)

“…<p>Significant decrease in the VCC-mediated IL-6 production in BMDMs from TLR2^-/- (A-B), C3H/HeJ (A-B), and TLR1^-/- (C-D) mice, as compared to that in BMDMs from the wild type (WT) mice. …”

Table 1_Short term heat stress alters the hematological, immunological, and plasma metabolomic responses of Florida Cracker sheep.xlsx by Makenzie Harrison (22152829)

“…Hematology analysis revealed a significant increase (P < 0.05) in neutrophil count and neutrophil percentage (%) and a decrease in lymphocyte percentage (%) at week 3 in the HT group. …”

<b>Triptolide alleviates </b><b>cognitive</b><b> impairment via </b><b>autophagy</b><b> and Akt/mTOR/p70S6K pathway in an APP/PS1 Alzheimer’s disease mouse model</b> by xinyao Qi (21686459)

“…<p dir="ltr">Alzheimer's Disease (AD) is characterized by cognitive decline and synaptic dysfunction, with amyloid-beta (Aβ) accumulation contributing significantly to disease pathology. …”

Table 1_Patient and donor antibody profiles in early COVID-19 convalescent plasma therapy in the COnV-ert trial.pdf by Andrea Alemany (11836601)

“…MB was associated with a significant decrease in cytophilic subclasses IgG1 and IgG3 to S and S2, and IgA to RBD, S and S2 in CCP units IgA to RBD, S and S2 in CCP units, without a reduction in neutralization titer and with a modest increase in IgG2 to RBD and S.…”

Steel slag-based silicate fertilizer suppresses grain cracking in brewer’s rice cultivar “Yamada-Nishiki” by Youshi Tazoe (20410017)

“…Moreover, the high-temperature treatment led to a significantly higher percentage of cracked grains, whereas silicate application resulted in a notably lower percentage. …”

Data Sheet 2_Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms.pdf by Min Chen (147733)

“…Moreover, RNA-seq analysis demonstrated that SF caused the gene expression profile of MI mice to shift toward that of sham mice, with a significant decrease in apoptosis-, ROS-, and inflammation-associated gene enrichment. …”

Presentation 1_Seasonal and spatial variations of nutrients and environmental effects under anthropogenic influence in Daya Bay, China.pdf by Jincheng Zhao (3625676)

“…A transformation has been observed in the dominant composition of dissolved inorganic nitrogen, shifting from ammonia to total oxidized nitrogen as the main component, which is mainly attributable to the decrease in aquaculture activities in Daya Bay over the last 3 years. …”

Data Sheet 1_Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms.pdf by Min Chen (147733)

“…Moreover, RNA-seq analysis demonstrated that SF caused the gene expression profile of MI mice to shift toward that of sham mice, with a significant decrease in apoptosis-, ROS-, and inflammation-associated gene enrichment. …”

Table 1_Characterization of glycogen-related glycoside hydrolase glgX and glgB from Klebsiella pneumoniae and their roles in biofilm formation and virulence.docx by Xinyue Liu (170148)

“…The deletion of the glgB gene resulted in a decrease in the growth rate of the bacteria and defected glycogen synthesis. …”

Image 1_The contribution of BTK signaling in myeloid cells to neuroinflammation.jpeg by Claudia Bassani (7235849)

“…Therapeutic intervention with evobrutinib ameliorated EAE severity and was associated with a significant modest decrease in the frequency of CNS-infiltrating proinflammatory macrophages. …”

<b>Egg rejection does not change with seasonal variation in risk of parasitism in two sympatric breeding cuckoo hosts</b> by Guo Zhong (15424978)

“…The area is mainly a karst landscape consisting of a mosaic of villages, farmland, scrublands, and barren slopes (Zhong <i>et al.…”

Comparative analysis of functional group effects on CO₂, CH₄, CO, and N₂ adsorption in UiO-66 and its derivatives by Prudhviraj Medikonda (20561356)

“…The selectivity of CO₂ over CH₄, CO, and N₂ showed that introducing larger and more complex functional groups caused a sudden decrease in selectivity with increasing temperature; this difference was more significant at lower temperatures and negligible at higher temperatures.…”