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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
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Regenerating axons are increased by ATRA and decreased by clodronate.
Published 2021“…Asterisks or “ns” above each column indicate the significance when compared to PBS control (row 1, gray), ATRA (row 2, green), or clodronate (row 3, red) with ANOVA and <i>post-hoc</i> Tukey tests. …”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”