Table1_Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data.DOCX by Luyang Su (20411552)

“…Unforeseen significant AEs such as unintended pregnancy (n = 623; ROR, 6.65; ROR025, 6.1; χ², 2,482.38; PRR, 6.41; EBGM, 5.69; EBGM05, 5.29), bone pain (n = 35; ROR, 13.78; ROR025, 9.4; χ², 311.2; PRR, 13.75; EBGM, 10.59; EBGM05, 7.69), gait disturbance (n = 34; ROR, 2.82; ROR025, 1.99; χ², 37.31; PRR, 2.88; EBGM, 2.7; EBGM05, 2.02), dental caries (n = 15; ROR, 23.16; ROR025, 12.32; χ², 204.26; PRR, 23.14; EBGM, 15.23; EBGM05, 8.98), decrease in blood pressure (n = 15; ROR, 3.88; ROR025, 2.29; χ², 29.35; PRR, 3.88; EBGM, 3.63; EBGM05, 2.33), and osteonecrosis (n = 9; ROR, 23.44; ROR025, 10.36; χ², 123.67; PRR, 23.43; EBGM, 15.35; EBGM05, 7.75) were identified as AEs that were not previously outlined in the prescribing information of the medication.…”

Effect of regional nerve block on tourniquet-related injury in pediatric patients undergoing lower limb surgery: a randomized controlled study by Qin Xia (1758646)

“…Additionally, patients in the PNB group had a significantly shorter time to first ambulation and a shorter hospital length of stay.…”

Supplementary file 1_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.docx by Christian Ayala-Ortiz (15255371)

“…</p>Discussion<p>This suggests that while litter inputs temporarily increase CO₂ emissions, they don’t sustain long-term acceleration of stored carbon decomposition or substantially decrease peat’s carbon store capacity. Our findings demonstrate how technological advancements in analytical tools can provide a more detailed view of carbon cycling processes in complex soil systems.…”

Table 2_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.docx by Hong Xu (71477)

“…Additionally, these offspring demonstrated a decreased likelihood of elevated homeostasis model assessment of insulin resistance (OR: 0.58; 95% CI: 0.34–0.98; P < 0.05). …”

Table 1_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.doc by Hong Xu (71477)

“…Additionally, these offspring demonstrated a decreased likelihood of elevated homeostasis model assessment of insulin resistance (OR: 0.58; 95% CI: 0.34–0.98; P < 0.05). …”

Quantification of faecal glucocorticoid metabolites as a measure of stress in the rock hyrax (Procavia capensis) living in an urban green space by Scheun, Juan (8229483)

“…Animal FID did not differ significantly between seasons but they did differ significantly between sections, and decreased in accordance with fGCM concentrations. …”

Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study by Emiko Otsuka (7519313)

“…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …”

Image 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf by Liang Sui (20912441)

“…DALYs and years of life lost (YLLs) rates generally decreased, with intervals of stabilization and minor increases, while years lived with disability (YLDs) showed significant fluctuations. …”

Presentation 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf by Liang Sui (20912441)

“…DALYs and years of life lost (YLLs) rates generally decreased, with intervals of stabilization and minor increases, while years lived with disability (YLDs) showed significant fluctuations. …”

Data Sheet 1_Treatment of bacterial biothreat agents with a novel purified bioactive lactoferrin affects both growth and biofilm formation.docx by Christian Xander (9120108)

“…Here, we show that Lactea Lf can significantly inhibit biofilm and decrease the overall growth in a dose dependent manner for all Burkholderia species tested. …”

Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation. by Hilary T. Brewis (11798006)

“…There was overlap found in all four groups: 1) genes that had increased mRNA expression and H2A.Z enrichment at their TSS in the HU-treated condition, 2) mRNA expression increased, while H2A.Z enrichment decreased, 3) mRNA expression decreased, while H2A.Z enrichment increased, and 4) genes where mRNA expression and H2A.Z enrichment at the TSS decreased after HU exposure. …”

Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Table 1_The immediate pain relief of low-level laser therapy for burning mouth syndrome: a retrospective study of 94 cases.docx by Wenxin Mu (9911610)

“…Significance<p>Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that seriously affects quality of life of patients. …”

Image 1_The immediate pain relief of low-level laser therapy for burning mouth syndrome: a retrospective study of 94 cases.tif by Wenxin Mu (9911610)

“…Significance<p>Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that seriously affects quality of life of patients. …”

A study of the mediating role of bedtime music in employment anxiety and sleep quality among college students DATA.xl by Xu Qiujian (19715689)

“…Specifically, β decreased from 0.583 to 0.53, and T decreased from 25.717 to 22.91 Nevertheless, employment anxiety still exhibited a substantial impact on sleep quality (β = 0.53; T = 22.91; P < 0.001).Conclusion: This study concludes that employment-related anxiety has a positive and significant effect on sleep quality. …”

From ice to flow: Tracing the transformation of glacial dissolved organic matter across a typical Tibetan Plateau glacier-lake-stream continuum by Yongqiang Zhou (11551027)

“…<p dir="ltr"><a href="" target="_blank">Mountain glaciers are melting at an accelerated rate due to global warming, thereby significantly altering proglacial and downstream hydrology</a>. …”

Data Sheet 1_Patient engagement in radiation oncology: a large retrospective study of survey response dynamics.docx by Bailey A. Loving (20573882)

“…MVA showed that higher socioeconomic disadvantage significantly decreased survey participation (ADI third tertile vs. first tertile OR=0.708, p<0.001), with each unit increase in ADI reducing the odds of completion by 1% (p<0.001). …”

Data Sheet 1_Prophylactic administration of lecithinized superoxide dismutase for a murine model of oxaliplatin-induced myelosuppression.pdf by Mikako Shimoda (9519493)

“…Background<p>Oxaliplatin, in combination with 5-fluorouracil and leucovorin, is a standard treatment for colorectal cancer and shows high efficacy. …”