Image 5_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

“…</p>Results<p>Three RCTs (IMpower150, jRCT2080224500, and ORIENT-31) comprising a total of 1529 patients were analyzed. The PIBC regimen significantly improved PFS (hazard ratio [HR]: 0.76 [0.66, 0.87], P < 0.0001), objective response rate (risk ratio [RR]: 1.36 [1.22, 1.51], P < 0.00001), and disease control rate (RR: 1.06 [1.00, 1.12], P = 0.04). …”

Table 1_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

“…</p>Results<p>Three RCTs (IMpower150, jRCT2080224500, and ORIENT-31) comprising a total of 1529 patients were analyzed. The PIBC regimen significantly improved PFS (hazard ratio [HR]: 0.76 [0.66, 0.87], P < 0.0001), objective response rate (risk ratio [RR]: 1.36 [1.22, 1.51], P < 0.00001), and disease control rate (RR: 1.06 [1.00, 1.12], P = 0.04). …”

Image 6_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

“…</p>Results<p>Three RCTs (IMpower150, jRCT2080224500, and ORIENT-31) comprising a total of 1529 patients were analyzed. The PIBC regimen significantly improved PFS (hazard ratio [HR]: 0.76 [0.66, 0.87], P < 0.0001), objective response rate (risk ratio [RR]: 1.36 [1.22, 1.51], P < 0.00001), and disease control rate (RR: 1.06 [1.00, 1.12], P = 0.04). …”

<b>Efficacy of </b><b>GLP-1-based Therapies on</b><b> </b><b>Metabolic Dysfunction-Associated Steatotic</b><b> Liver Disease and </b><b>Metabolic Dysfunction-Associated</b><b> Stea... by Yahao Wang (21291242)

“…Overall, GLP-1RAs treatment for a median of 24 weeks demonstrated a significant reduction in LFC by 5.21%, with the retatrutide displaying the most obvious treatment effects. …”

Statistical analysis of the AUC measurement. by Esra Ayan (21156015)

“…The mean AUC decreased in both samples.</p> <p>(TIF)</p>…”

Data Sheet 1_Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective T... by Xinxin Ying (21507500)

“…Survival analysis revealed a significant correlation between elevated TIM-3 expression and decreased patient survival. …”

<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de... by Ricardo Riveros (22484566)

“…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …”

Raw data for ASV analysis. by Fittree Hayeeawaema (20775941)

“…Treatment with live and heat-killed Ln.m significantly reduced BUN and creatinine levels in CKD mice (<i>p</i> < 0.01 and <i>p</i> < 0.05). …”

Raw data. by Fittree Hayeeawaema (20775941)

“…Treatment with live and heat-killed Ln.m significantly reduced BUN and creatinine levels in CKD mice (<i>p</i> < 0.01 and <i>p</i> < 0.05). …”

Timeline for study enrollment. by Saeun Park (20410160)

“…</p><p>Conclusions</p><p>Negative COVID-19 experiences were significantly associated with more severe depression and anxiety in Ugandan caregivers, regardless of their children’s malaria status. …”

Dataset used in the manuscript. by Saeun Park (20410160)

“…</p><p>Conclusions</p><p>Negative COVID-19 experiences were significantly associated with more severe depression and anxiety in Ugandan caregivers, regardless of their children’s malaria status. …”

mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t... by Shanhe Liu (5251313)

“…In LSCs, <i>BCL2</i> mRNA level significantly decreased (p = 0.0102) and <i>CDKN1B</i> level significantly increased using 75 µM CoCl₂ treatment. …”

Investigating the Impact of Base Pair Mismatches on Cas13d Cleavage Efficiency Using Molecular Dynamics Simulations by Ye Liu (296340)

“…However, the presence of mismatches significantly undermines the cleavage efficiency of Cas13d to target RNA. …”

Cell proliferation of limbal epithelial cells (LECs) after 20-minute treatment with travoprost at concentrations ranging from 0.039 μg/mL to 40 μg/mL, using the ELISA-BrdU (colorim... by Shuailin Li (11907158)

“…<p>LEC proliferation decreased significantly following treatment with 20 μg/mL and 40 μg/mL concentrations of travoprost (p = 0.029 and p = 0.006, respectively).…”

Individual Conditional Expectation (ICE) plot showing the predicted probability of BMI across age, sex and self-awareness. by Probir Kumar Ghosh (6947282)

<b>Role of the Chaperone ClpB in</b><b> </b><b>Mycoplasma bovis</b><b> Virulence: Implications for </b><b>stress response, a</b><b>dhesion, </b><b>b</b><b>iofilm </b><b>d</b><b>eve... by Hui zhang (22187170)

“…Phenotypic characterization revealed that ClpB disruption attenuated key virulence attributes, including: impaired host cell adhesion capacity, significant reduction in biofilm formation (p<0.01), diminished induction of proinflammatory cytokines (IL-1β, IL-6, TNF-α) in infected BoMac cells, decreased extracellular nuclease activity. …”

<b>Selective Reduction of Ca</b>^{<strong>2+</strong>}<b>-Independent Phospholipase A</b>_{<strong>2</strong>}<b>b</b><b> (iPLA</b>_{<strong>2</strong>}<b>b... by Abdulaziz Almutairi (9584768)

“…These outcomes are associated with a significant reduction in T1D. Further, inhibition of select proinflammatory lipid signaling pathways reduces M1-like MF polarization and adoptive transfer of M2-like MF reduces NOD T1D incidence, suggesting a mechanism by which iDLs impact T1D development. …”

Data from paper: <i> Twenty-year effect of sewage-sludge fertilization in a Mediterranean </i><i>grassland: Impact on species composition, functional groups and interrelation with... by Mercedes Valerio (22631942)

“…We analyzed the vegetation dynamics of a grazing-excluded, semi-natural Mediterranean grassland over 20 years in response to a single sludge fertilization event. …”

Comparative Analysis of Gut Microbiota in Collegiate Swimmers Following Changes in Exercise by Jarrad Hampton-Marcell (695263)

“…Coinciding with the decrease in training volume, the microbial community structure showed a significant decrease in overall microbial diversity, a decrease in microbial community structural similarity, and a decrease in the proportion of the bacterial genera <i>Faecalibacterium</i> and <i>Coprococcu</i>s. …”

Table 1_The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis.docx by Lifeng Wang (121568)

“…The treatment resulted in a significant decrease in SCORAD score among children with moderate to severe AD, but not in subjects with mild AD.…”