Effects of Kylo-0603 on body weight, organ weight, and body fat content. حسب Xueqin lu (22250795)

The body weight and cholesterol levels of the mice were recorded before the administration of the drug. حسب Xueqin lu (22250795)

The trends of cholesterol metabolism-related gene expression in liver tissue. حسب Xueqin lu (22250795)

Hazard ratios for Sex across age based on unadjusted (A) and adjusted (B) Cox model. Note: shaded areas representing the 95% confidence intervals; green bars indicating the distrib... حسب Hui Ouyang (245739)

Deviatoric stress-strain curves of numerical samples composed of elongated ellipsoids with different particle morphologies and particle sizes. حسب Yongfeng Zhu (7361045)

Numerical samples composed of elongated ellipsoids before and after triaxial compression. حسب Yongfeng Zhu (7361045)

The force chain distributions of different numerical samples composed of elongated ellipsoids with different particle morphologies and particle sizes before shearing and after load... حسب Yongfeng Zhu (7361045)

Different ellipsoidal particles with De = 6.30 mm used in the discrete element simulations. حسب Yongfeng Zhu (7361045)

Kylo-0603’s EC50 & tissue levels. حسب Xueqin lu (22250795)

DIO Mice Liver Staining. حسب Xueqin lu (22250795)

The Fibrosis scoring by Sirius Red staining and SHG/TPEF. حسب Xueqin lu (22250795)

Pharmacological efficacy of Kylo-0603 in MASH mouse models (F2 ~ 3). حسب Xueqin lu (22250795)

After 8 weeks of treatment, body fat analysis and bone mineral density testing of mice in each group. حسب Xueqin lu (22250795)

Plasma cholesterol and LDL-C levels. حسب Xueqin lu (22250795)

The Chol and TG content in liver homogenates of the mice in each group after 2 and 10 weeks of drug intervention. حسب Xueqin lu (22250795)

Hematoxylin and eosin (H&E) staining, Sirius Red staining, and Oil Red staining of liver tissues from mice in each group after 8 weeks of treatment with either vehicle or Kylo-0603... حسب Xueqin lu (22250795)

Effect of Kylo-0603 drug on the reversal of steatosis and inhibition of fibrotic process in liver tissues of the MASH mouse models (F2 ~ 3), analyzed by SHG/TPEF microscopy combine... حسب Xueqin lu (22250795)

β-NAD increases intracellular cAMP concentration via soluble adenylyl cyclase, but this pathway is not essential for the relaxing effect. حسب Innokentij Jurastow (22430601)

"…<p>(A, B) Recording of intracellular cAMP concentration in HBSMC via FRET, with low FRET ratio indicating high cAMP concentration. β-NAD and isoproterenol cause a decrease in FRET ratio, reflecting rise in intracellular cAMP concentration. …"

General procedure for the synthesis of Kylo-0603. حسب Xueqin lu (22250795)

Interpretation of findings of the present study. حسب Rayane Brinck Teixeira (6676529)