Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents
Published 2025“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”
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AZ10606120 treatment significantly increased cytotoxicity and reduced cell number in a dose-dependent manner.
Published 2025“…Cell numbers were significantly decreased in cells after treatment with AZ10606120 (50µM) compared to both temozolomide (TMZ; 50µM) treatment and untreated controls. …”
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1471
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a) Number weighted mean volume of AEII during postnatal development and in adults. There are no volume alterations before and at the end of bulk alveolarization. A significant increase was determined in adults compared to 3 and 7 days old pups. b) Size of AEII presented as V<sub>S</sub>-ratioAEII during postnatal lung development into adulthood. Before and during bulk alveolarization there are no size changes. Adults show a significant increase compared to values before and at onset of alveolarization. c) Number weighted mean volume of AEII per lung volume during postnatal development and in adults. The highest values are seen before alveolarization. During alveolarization the quotient decreases and reaches significance compared to 3 days old pups at postnatal day 21....
Published 2025“…During alveolarization the quotient decreases and reaches significance compared to 3 days old pups at postnatal day 21. …”
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