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significantly smaller » significantly higher (Expand Search), significantly lower (Expand Search), significantly greater (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
smaller decrease » small decrease (Expand Search), marked decrease (Expand Search), smaller areas (Expand Search)
affect decrease » effects decreased (Expand Search)
significantly smaller » significantly higher (Expand Search), significantly lower (Expand Search), significantly greater (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
smaller decrease » small decrease (Expand Search), marked decrease (Expand Search), smaller areas (Expand Search)
affect decrease » effects decreased (Expand Search)
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<i>SEL1L</i> variants affect proteasome inhibition sensitivity.
Published 2025“…<b>(B)</b> When treated with 1μM BTZ, the <i>NGLY1 + /-</i> larvae show a <i>SEL1L</i> genotype-dependent decrease in size. While <i>SEL1L</i><sup><i>+/+</i></sup> showed no change between DMSO (19.65 ± 5.98) and BTZ (17.88 ± 4.32), <i>SEL1L</i><sup><i>S780P/+</i></sup> (DMSO 21.03 ± 3.42, BTZ 16.45 ± 3.65, p < 0.0001) and <i>SEL1L</i><sup><i>Δ806-809/+</i></sup> (DMSO 24.92 ± 3.39, BTZ 20.08 ± 2.69, p = 0.001) genotypes were smaller when treated with BTZ compared to DMSO treated larvae. …”
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