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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
mean decrease » a decrease (Expand Search)
decrease n » decrease _ (Expand Search), decrease i (Expand Search), decreases _ (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
altered decrease » altered release (Expand Search), observed decrease (Expand Search), teer decrease (Expand Search)
mean decrease » a decrease (Expand Search)
decrease n » decrease _ (Expand Search), decrease i (Expand Search), decreases _ (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…<p>(A-B) GCase, (C-D) gluocosylceramide (GlcCer), and (E-F) glucosylsphingosine (GlcSph) levels measured in whole brain homogenate and liver homogenate of C57Bl/6 wild type (WT) and <i>GBA1</i> D409V KI heterozygous (HET) mice at 5 months of age (n = 10/age). (A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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Image_3_Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.tif
Published 2020“…The expression of both GN and UGN was significantly decreased in the CSDS mice relative to controls. …”
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Image_2_Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress.tif
Published 2020“…The expression of both GN and UGN was significantly decreased in the CSDS mice relative to controls. …”