Supplementary Material for: Patients with Opioid Use Disorder Choosing Treatment with Extended-Release Naltrexone: A 6-Months Naturalistic Study by Brenna I.H. (19773549)

“…The majority of the MITT population (84; 60.9%) completed 24 weeks of treatment in the study. There was a significant decrease in the overall use of opioids (p<0.001) and the use of alcohol and other illicit substances was low. …”

Data from: Decade-long bird trends in China: Stable species richness but increasing biotic homogenization by Jiekun He (20964269)

“…Taxonomic multiple-site beta diversity decreased over time (P < 0.01), indicating a trend towards biotic homogenization. …”

Penguin ease of transport for real vs. fully-compensated travel vectors relative to the ground during the return journey with respect to depth use and prey acquisition. by Richard M. Gunner (12652026)

“…The absence of a triangle indicates no significant difference at that interval. <b>(b)</b> Mean maximum dive depth (±1 SE, in m) and mean prey pursuit rate (±1 SESE, pursuits s⁻¹), plotted at 0.05 intervals of the return journey’s proportion of distance travelled. …”

Table 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.docx by Sylvia Cheptoo (22040249)

“…Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”

Image 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.tiff by Sylvia Cheptoo (22040249)

“…Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”

Data Sheet 1_Platelet count and retinopathy of prematurity, a systematic review and meta-analysis.docx by Qian Zeng (2866592)

“…The pooled analysis indicated a significant decrease in mean platelet count among the ROP group compared to the non-ROP group (mean difference: −18.65, 95% confidence interval: −22.80 to −14.50, P < .00001). …”

Alleviation of Nanoplastic Stress in Rice: Evidence from Biochemical, Cytological, Physiological, and Transcriptome Analysis by Jiacheng Jin (11480055)

“…Moreover, SEM and TEM showed that S18 exhibited a better-protected cellular structure than MXZ. Furthermore, physiological parameters, including photosynthetic pigments, antioxidant enzyme activities, lignin contents, Mo contents, along with H₂O₂ and MDA contents (decrease by 9 and 19% under nMo+NP compared to NP treatment), have shown that nMo was capable of alleviating NP stress, and S18 was better in maintaining physiological homeostasis. …”

Effect of soil salinity on cotton cultivation and the potential for introducing <i>Amaranthaceae</i> halophytes in the Yellow River Delta, China by Hiroshi Takagi (271173)

“…Levels of major (K⁺, Ca²⁺ and Mg²⁺) or minor (Fe²⁺, Mn²⁺, Zn²⁺ and Cu²⁺) essential elements were not significantly decreased by the increase of field EC in any plant species, except for K⁺ in <i>S</i>. …”

Table 1_Adjuvant melatonin therapy during exercise prescription in breast cancer survivors on physical and anthropometric parameters, quality of life, and hormonal response. A rand... by Ana M. Celorrio San Miguel (21583961)

“…Finally, testosterone/cortisol ratio decreased in both groups at the end of intervention, but the difference was not statistically significant (p > 0.05).…”

Data Sheet 1_Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators.pdf by Michael Hecker (51971)

“…A gene expression signature that is characteristic of CD4⁺ cytotoxic T lymphocytes (CD4-CTLs) was found to be elevated at baseline in non-responders to apheresis, although this could not be validated with statistical significance (n=19 MS patients).</p>Conclusion<p>Our data reveal that therapeutic apheresis in MS rapidly leads to a significant decrease in IgG reactivities against EBNA1 (391-410) and cross-reactive targets such as GlialCAM (370-389) and also has an impact on the gene expression of B cells and T cells. …”

Tuning curve sharpening and familiarity suppression. by Weifan Wang (4669081)

“…Both learning rules result in a statistically significant decrease in the SI. The inset shows the convergence of the distribution’s mean over training epochs. …”

Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…</p>Discussion:<p>While some associations were statistically significant, the small effect sizes and lack of associations observed in the whole UK Biobank population suggest that CYP3A5 variation likely has no impact on blood pressure related phenotypes in a general population. …”

Data Sheet 1_Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging.pdf by Iuliia Golovynska (18880049)

“…</p>Results<p>In neurons exposed to Aβ, the number of mitochondria increases by 2.6 times, while their total volume decreases by 2.2 times. As a result, the volume and surface area per mitochondrion decrease by 6-fold and 4-fold, respectively. …”

Supplementary file 1_Effects of Bifidobacterium on metabolic parameters in overweight or obesity adults: a systematic review and meta-analysis.docx by Junmei Huang (723403)

“…The experimental group receiving Bifidobacteria exhibited a marked decrease in weight (WMD: −0.607 kg; 95% CI: −0.910, −0.303, I² = 11.9%) and BMI (WMD: −0.214 kg/m²; 95% CI: −0.259, −0.169, I² = 4.1%) in contrast to the control, although the significant effect was not noted on WC. …”

Presentation 1_Seasonal and spatial variations of nutrients and environmental effects under anthropogenic influence in Daya Bay, China.pdf by Jincheng Zhao (3625676)

“…<p>Nutrients are crucial factors for the growth of phytoplankton, and their biogeochemical processes directly impact marine biodiversity. In this study, based on two cruise observations in spring and summer of 2024, the seasonal and spatial variations of nutrients, chlorophyll a, and other ecological indicators in Daya Bay were explored. …”

Image 2_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…In this study, we utilized an in vitro human umbilical cord blood-derived CD34⁺ cell-based erythroid differentiation system, alongside a murine model, to investigate the impact of PLK1 inhibitors on erythropoiesis. Our results indicate that PLK1 inhibitors, specifically GSK461364 and BI6727, significantly suppress the proliferation of erythroid cells, resulting in G2/M phase cell cycle arrest, increased apoptosis in erythroid cells, and the formation of abnormally nucleated late-stage erythroblasts. …”

Table 1_Flammulina velutipes mycorrhizae dietary fiber attenuates the development of obesity via regulating lipid metabolism in high-fat diet-induced obese mice.xlsx by Fengjuan Jia (703605)

“…</p>Methods<p>Herein, we conducted a comprehensive study utilizing HFD-induced C57BL/6J mice as an obesity model to investigate the impact of Fv-DF on liver lipid accumulation.</p>Results<p>The study, which included an evaluation of Fv-DF on a high-fat diet (HFD)-induced obese mice, revealed that Fv-DF supplementation can effectively decrease weight gain, improve serum lipid levels, and reduce fat deposition in adipose tissues. …”

Table1_Tle6 deficiency in male mice led to abnormal sperm morphology and reduced sperm motility.docx by Kousuke Kazama (19937214)

“…In this study, we generated a novel Tle6 knockout mouse model using CRISPR-Cas9 to examine the impact of Tle6 mutations on male fertility. Tle6 knockout males exhibited a reduced total sperm count compared to wild-type mice, with a marked decrease in highly motile sperm. …”

Table 1_A growing degree day model determines the effect of temperature stress on diverse chickpea genotypes.docx by Cara Jeffrey (20437895)

“…These metrics allowed greater differentiation between environments when compared to a count of the number of calendar days required for each cultivar to reach a set life stage (flowering and maturation), allowing more accurate investigation the impacts of high temperature stress. It was also determined that loss of yield and a decrease in seed size was significantly correlated with high GDD and SDD, though seed size had less environmental plasticity (variability) compared to yield, and therefore higher stability under stress. …”

Table1_Bidirectional two-sample Mendelian randomization analysis investigates causal associations between cathepsins and inflammatory bowel disease.DOCX by Na Wang (193263)

“…</p>Results<p>The forward MR analyses showed no significant association between cathepsins and IBD. …”