Data&Code.zip by Yan Li (8859833)

“…<p dir="ltr">Affected by numerous uncertainties, climate change is a critical issue linked to carbon emissions that warm the planet. During the COVID-19 global pandemic, public health measures significantly influenced carbon emissions. …”

Image 2_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 3_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 1_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Image 4_Effects of oral gavage with periodontal pathogens and plaque biofilm on gut microbiota ecology and intestinal tissue architecture in mice: a mechanistic study.jpg by Lan Huang (11591)

“…In the BF group, only TNF-α expression demonstrated a significant increase (P < 0.01). The expression of occludin is significantly reduced in the F/P/BF group, with the most pronounced decrease observed in the P group (P < 0.01). …”

Data_Sheet_1_Regulation of intestinal flora by Suaeda salsa extract ameliorates hyperglycemia in a mouse model of type 2 diabetes mellitus.ZIP by Xuemei Yin (751017)

“…Moreover, 4-week body weight, FBG, AUC of OGTT, GSP, as well as intestinal acetic and butyric acid were significantly better in the SSE-L than in the MET group (p < 0.05). …”

Table 2_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx by Amirmohammad Afsharnia (22569827)

“…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …”

Image 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.jpeg by Amirmohammad Afsharnia (22569827)

“…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …”

Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes... by figshare admin karger (2628495)

“…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …”

Effects and Potential Risks of Chiral Penflufen on Pickled Cowpea: Combined Microbiome and Metabolomics by Chao Guo (163795)

“…<i>Rac</i>-penflufen treatment significantly decreased the relative abundance of <i>Lactiplantibacillus</i> while increasing <i>Weissella</i>, but the opposite effects were found in <i>R</i>- and <i>S</i>-penflufen treatments. …”

Data Sheet 1_Effects of Ophiopogon japonicus oligosaccharides on type 2 diabetes in rats via modulation of gut microbiota and metabolites.docx by Tingyu Yang (10686507)

“…Additionally, OJO significantly reduced acetic acid and propanoic acid levels. …”

Table 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx by Amirmohammad Afsharnia (22569827)

“…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …”

Table 1_Specific inhibition of glutamine synthase involved in the metabolic pathway of amino acids is associated with anti-arthritic effects of sinomenine hydrochloride.docx by Gejing Li (18948236)

“…Experimental validation confirmed that SH (50–200 μM) significantly inhibited GS activity and GLUL expression and consequently decreased glutamine levels in RA-FLS. …”

Table 1_Association of serum chemokine (C–C motif) 21 and receptor (C–C motif) 7 with Hashimoto’s thyroiditis——a preliminary clinical investigation.docx by Xiaoting Gui (22516922)

“…We analyzed the between-group differences in the serum CCL21 and CCR7 levels which were quantified by enzyme-linked immunosorbent assay in all subjects.</p>Results<p>Compared with the healthy control group, the Hashimoto’s thyroiditis group had significantly increased serum CCL21 [154.92 (147.01, 165.34) vs 123.74 (118.02,129.22), p<0.001] and CCR7 [19.15 (18.19, 19.71) vs 16.47 (15.88, 17.14), p<0.001], decreased free triiodothyronine, and increased thyroid stimulating hormone, TgAb, and TPOAb. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…The weight of mushrooms produced from all agro-forest waste substrates was significantly lower than that of the control group, decreasing by 18.96 to 53.88%. …”

Data Sheet 1_Divergent profiles of rhizosphere soil carbon and nitrogen cycling in Pinus massoniana provenances with different types of carbon storage.docx by Zichen Huang (6587885)

“…</p>Results<p>Our findings revealed a significant increase in the relative abundance of Acidobacteriota and Ascomycota by 23 and 61%, respectively, whereas Basidiomycota significantly decreased by 8% in the rhizosphere of P. massoniana provenances with high carbon storage compared with those with low carbon storage. …”

Table 1_Electroacupuncture improves scopolamine hydrobromide induced dry eye in mice via inhibiting ocular surface inflammation and regulating the HMGB1-related signaling pathways.... by Xia Wu (203682)

“…The levels of HMGB1, RAGE, TLR2, TLR4, and IL-6 were significantly decreased while IL-10 level was significantly increased after EA treatment, indicating that EA may improve dry eye surface inflammation by inhibiting HMGB1-related signaling pathways.…”

Table 2_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Data Sheet 1_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.xlsx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”

Table 3_Impact of chemoradiotherapy for first primary lung cancer on the prognosis and re-chemoradiotherapy sensitivity of second primary lung cancer.docx by Zhe Chen (196097)

“…</p>Results<p>The competitive risk model indicated that FPLC radiotherapy and chemotherapy did not significantly change the risk of developing SPLC. However, the Cox proportional hazards model revealed that FPLC radiotherapy was associated with decreased overall survival (OS; HR=1.251, P<0.001) and cancer-specific survival (CSS; HR=1.228, P=0.001) in patients with SPLC. …”