Data Sheet 1_Spinal cord injury enhances lung inflammation and exacerbates immune response following exposure to LPS.docx by Bradford C. Berk (6647084)

“…Infiltration of Ly6G/C positive neutrophils and macrophages was significantly higher in SCI mice lungs post-LPS exposure. …”

DataSheet1_Cellular and transcriptomic changes by the supplementation of aged rat serum in human pluripotent stem cell-derived myogenic progenitors.DOCX by Sin-Ruow Tey (19848060)

“…</p>Results<p>We found that aged rat serum supplementation significantly reduced cell proliferation and increased cell death in both ESC- and iPSC-derived myogenic progenitors. …”

Supplementary file 1_Disentangling the functioning of native soil microbes in enhancing nutritional value of Aloe vera and soil health parameters.docx by Neha Singh Chandel (20944718)

“…Furthermore, bacterial inoculation significantly enhanced soil enzymatic activity and increased the soluble nitrate and phosphate content in the experimental soil. …”

Table 1_CheekAge, a next-generation epigenetic buccal clock, is predictive of mortality in human blood.xlsx by Maxim N. Shokhirev (2391904)

“…To better understand the relative importance of each CheekAge input in blood, we iteratively removed each clock CpG and re-calculated the overall mortality association. The most significant effect came from omitting the CpG cg14386193, which is annotated to the gene ALPK2. …”

Table 8_Integrated genomics, metagenomics and metatranscriptomics to reveal the biocontrol mechanism of Bacillus velezensis JY10 against tobacco target spot disease.xlsx by Wenjuan Yang (174250)

“…Metagenomic profiling showed that JY10 treatment had no significant influence on tobacco phyllosphere and rhizosphere microbiome structure, however, it significantly increased the relative abundance of beneficial microbes, including Bacillus, Pseudonocardia, and Pseudomonas. …”

Table 4_Development of a ferroptosis-related signature and identification of NOTCH2 as a novel prognostic biomarker in pancreatic cancer.xlsx by Siyi Zhang (577078)

“…A prognostic signature was constructed using LASSO and Cox regression analysis. The role of a key gene, NOTCH2, was investigated through somatic mutation, functional enrichment, immune infiltration, and drug sensitivity analysis. …”

Table2_MAPK and phenylpropanoid metabolism pathways involved in regulating the resistance of upland cotton plants to Verticillium dahliae.xls by Mingli Zhang (406266)

“…</p>Results<p>The results revealed a significant differential expression of genes in the two cotton cultivars post V. dahliae infection, with the number of DEGs in JK1775 being higher than that in Z8 at different infection stages of V. dahliae. …”

Data Sheet 1_CD44 and CLDN3 as immune-metabolic regulators in acute pancreatitis: a multi-modal transcriptomics study and experimental validation.pdf by Xinwei Wang (352488)

“…Then, single-sample gene set enrichment analysis revealed CLDN3 and CD44 were significantly correlated with immune-related structural remodeling and immune infiltration patterns. …”

DataSheet1_Caffeic acid O-methyltransferase from Ligusticum chuanxiong alleviates drought stress, and improves lignin and melatonin biosynthesis.docx by Enxia Huang (12248422)

“…Under drought conditions, LcCOMT expression was significantly upregulated. Overexpression of LcCOMT gene in Arabidopsis plants conferred enhanced drought tolerance, characterized by elevated lignin and melatonin levels, increased chlorophyll and carotenoid content, heightened activities of antioxidant enzymes peroxidase (POD), catalase (CAT), and superoxide dismutase (SOD), and reduced malondialdehyde (MDA) and hydrogen peroxide (H₂O₂) accumulation. …”

Image 3_Deciphering differences in microbial community characteristics and main factors between healthy and root rot-infected Carya cathayensis rhizosphere soils.jpg by Wei Fang (116739)

“…</p>Results<p>We found that the pH, soil organic carbon(SOC), available nitrogen (AN), available phosphorus (AP), available potassium (AK),N-acetyl-β-D-glucosaminidase (NAG) β-glucosidase (BG), fungal gene copy number, bacterial community diversity and network complexity of the diseased soil were significantly lower (p < 0.05), while Fusarium graminearum copies number levels increased (p < 0.05). …”

Table 1_Development of a ferroptosis-related signature and identification of NOTCH2 as a novel prognostic biomarker in pancreatic cancer.xlsx by Siyi Zhang (577078)

“…A prognostic signature was constructed using LASSO and Cox regression analysis. The role of a key gene, NOTCH2, was investigated through somatic mutation, functional enrichment, immune infiltration, and drug sensitivity analysis. …”

Table 3_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx by Hanlin Yu (17776399)

“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”

DataSheet1_Deciphering heat wave effects on wheat grain: focusing on the starch fraction.zip by Rita Pereira (3854464)

“…Starch granule size distribution and shape were significantly altered by HW treatment, revealing an increase of A-type granules in Ardito and an opposite effect in Magueija and Bancal, while Antequera remained stable. …”

Image 1_Integrated genomics, metagenomics and metatranscriptomics to reveal the biocontrol mechanism of Bacillus velezensis JY10 against tobacco target spot disease.jpeg by Wenjuan Yang (174250)

“…Metagenomic profiling showed that JY10 treatment had no significant influence on tobacco phyllosphere and rhizosphere microbiome structure, however, it significantly increased the relative abundance of beneficial microbes, including Bacillus, Pseudonocardia, and Pseudomonas. …”

Image1_MAPK and phenylpropanoid metabolism pathways involved in regulating the resistance of upland cotton plants to Verticillium dahliae.tif by Mingli Zhang (406266)

“…</p>Results<p>The results revealed a significant differential expression of genes in the two cotton cultivars post V. dahliae infection, with the number of DEGs in JK1775 being higher than that in Z8 at different infection stages of V. dahliae. …”

Table 1_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx by Hanlin Yu (17776399)

“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”

DataSheet1_Lapatinib-induced enhancement of mitochondrial respiration in HER2-positive SK-BR-3 cells: mechanism revealed by analysis of proteomic but not transcriptomic data.ZIP by Dmitry Kamashev (11493274)

“…<p>Dual inhibitors of HER2 and EGFR, such as lapatinib, have shown significant efficacy for the therapy of HER2-positive breast cancer. …”

Table 4_Exploring common circulating diagnostic biomarkers for sleep disorders and stroke based on machine learning.xlsx by Hanlin Yu (17776399)

“…We need to further investigate the functional role of these genes and their potential in developing targeted therapies for SD and stroke patients.…”

CPSF6-NLS chimeras display cell-type specific phenotypes. by Nicholas Rohlfes (20577485)

“…WT HIV-1 infection was determined by luciferase reporter gene expression. Notably, T cells expressing CPSF6-SV40 NLS were significantly less infectable than corresponding HeLa cells, while CPSF6-SV40 NLS-expressing THP-1 cells supported 100% infection. …”

Table 1_Bacillus velezensis 20507 promotes symbiosis between Bradyrhizobium japonicum USDA110 and soybean by secreting flavonoids.xlsx by Yunqing Cheng (716812)

“…Flavonoids in B. velezensis fermentation broth were identified via mass spectrometry, and rutin’s regulatory effects on B. japonicum nodulation genes (NodD1/NodD2) were tested in coculture.</p>Results<p>Co-inoculation significantly increased nodulation, biomass, and N content per plant compared to single inoculations across all N levels. …”