Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio... by Man Han (8444859)

“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”

Table_1_Insights into the salt levels in bread offers in Slovenia: trends and differences.docx by Saša Kugler (20554580)

“…In addition, a significant difference was observed between white wheat bread sold in large retail shops and smaller bakeries, where a higher salt content was observed.…”

Data Sheet 1_New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis.docx by Ekaterina Semina (12152564)

“…The study represents the first attempt to explore the role of T-cadherin in COVID-19 pathogenesis as well as its implications in pulmonary fibrosis and endothelial dysfunction. First, we revealed a significant decrease in T-cadherin expression in post-mortem lung samples from COVID-19 patients. …”

Figure 4 from Photoacoustic Tomography Detects Response and Resistance to Bevacizumab in Breast Cancer Mouse Models by Isabel Quiros-Gonzalez (14952835)

“…<b>C,</b> Conversely, the Bev-R group trend toward a significant decrease in SO₂^MSOT, with no significant change in normalized THb observed. …”

Data Sheet 1_Antimony-resistant PGPR mitigates Sb toxicity and accumulation in peppers by restructuring rhizosphere microorganisms.docx by Xiangquan Sheng (22345987)

“…Microbiota analysis revealed that inoculation enriched stress-responsive bacterial phyla, such as Proteobacteria and Actinobacteria, as well as key functional genera associated with Sb tolerance (e.g., Ramlibacter) and nutrient cycling (e.g., Nitrospira), despite a decrease in alpha-diversity. Co-occurrence networks analysis indicated that inoculation significantly enhance node connectivity and mean degree in rhizosphere bacterial networks, reflecting an increase in structural complexity, especially under severe Sb stress (1,000 mg/kg). …”

Differentially abundant proteins in the haemolymph.  by Louise M. Coates (22298169)

“…<p>Volcano plots of the differentially abundant proteins in the haemolymph between infected and uninfected crickets <b>(a)</b>; infected and post-infected crickets <b>(b)</b>; post-infected and uninfected crickets <b>(c)</b>; dehydrated and hydrated crickets <b>(d)</b>; dehydrated and re-hydrated crickets <b>(e)</b>; and re-hydrated and hydrated crickets <b>(f)</b>.Proteins with non-significant differential abundance are represented by circles (grey), proteins with a significant increase in abundance in the first group are represented by triangles (black) and proteins with a significant decrease in abundance in the first group are represented by squares (black). …”

SERCA is required for Ca²+ transients at E5.5. by Matthew J. Stower (22379321)

“…DMSO treated embryos had a significant decrease in transients (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test; baseline vs. 30 min DMSO <i>p</i> > 0.05), but thapsigargin almost completely abolished transients to a significant effect (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, baseline vs. 30 min 10 nM thapsigargin <i>p</i> ≤ 0.001), that was significantly lower than DMSO controls (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, 30 min DMSO vs. 30 min 10 nM thapsigargin: <i>p</i> ≤ 0.001). …”

Supplementary file 1_Drug utilization study of antiparkinsonian medication in Romania during 25 years.pdf by Camelia Bucsa (12005078)

“…Trihexyphenidyl was the main anticholinergic prescribed with a maximum utilization of 0.82 DDD/TID in 2000 followed by a slight decrease until 2022 (0.56 DDD/TID). …”

Table 1_Modulatory effects of black jujube melanoidins on gut microbiota and metabolic pathways in high-fat diet-induced obesity.docx by Xi Che (21248720)

“…MLD also protected the liver, as evidenced by a 16.4% decrease in alanine aminotransferase (ALT) levels and a 29.6% decrease in aspartate aminotransferase (AST) levels (p < 0.05). …”

Data Sheet 1_Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis.docx by Rita Spathis (187690)

“…</p>Results<p>Viral load was significantly increased by 77-fold in white blood cells after two rAAV9-microdystrophin doses compared to mice receiving a single dose. …”

Data Sheet 1_Comparison of trend analysis of varicella zoster disease burden between China and the world 1990–2021 and disease burden forecast 2030.csv by Zhichun Chang (18594517)

“…The trends in ASIR and ASPR were notably influenced by age, while ASMR and ASDR exhibited a significant increasing trend with age. Projections indicate that the ASDR of varicella zoster in China will continue to decrease by 2030, while the ASIR, ASPR, and ASMR are expected to remain stable.…”

<i>Supporting data for “Microstructure and orientation control of electro-deposited copper and its application in advanced electronic packaging”</i> by Cong Chen (10332860)

“…To satisfy these needs, a unique composite Cu structure is developed by incorporating a nanograin structure into the (111)-oriented coherent nanotwinned copper. …”

Table 1_Elucidating the effects of nine-steaming-nine-drying on the morphology, metabolomic profile, and active ingredients of Polygonatum sibiricum Redouté.xls by Rui Wang (52434)

“…These alterations resulted in darker coloration, as evidenced by a significant decrease in L* values, elimination of tongue-numbing effects, enhanced sweetness, and improved quality of P. sibiricum Red. …”

DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP by Huadong Ke (19937268)

“…Furthermore, Berubicin exhibited a particularly high proportion of blood and lymphatic system disease AEs, reaching 45.6%, which was significantly greater than those observed for the other two drugs.…”

<b>The moderating effect of financial literacy on risk preferences and time preferences</b> by Calvin Mudzingiri (22188109)

“…Additionally, the study concluded that time preferences significantly moderate financial literacy. An increase in financial literacy is associated with a decrease in time preferences, indicating that as financial literacy rises, subjects become more patient. …”

Data Sheet 1_The impact of small food workshops management regulations on aflatoxin B1 in home-made peanut oil and the liver function of high-consumption area residents: an interru... by Jiangbo Lei (20457626)

“…The implementation of SFWMR was associated with a significant reduction in AFB₁ concentrations in HMPO, showing an immediate decrease of 2.865 μg/kg (P = 0.006) and a sustained annual reduction of 2.593 μg/kg (P = 0.034). …”

DataSheet1_Chronic exposure to inhaled vaporized cannabis high in THC suppresses Adderall-induced brain activity.zip by Jack M. Ognibene (19830132)

“…</p>Results<p>Mice exposed to cannabis when compared to placebo showed a decrease in brain activation to Adderall. The blunted Adderall response was characterized by a decrease in positive BOLD signal and increase in negative BOLD. …”

Numerical study on crack coalescence mechanism of rock specimens containing double parallel cracks by Wu Junyu (22515272)

“…Additionally, the crack coalescence mode shifts from a shear mode to a tensile mode. Furthermore, a decrease in rock bridge length facilitates crack coalescence.…”

Updated poaching trends until 2024 for West Coast rock lobster by Anabela Brandao (10003679)

“…In the case of the northern Super-areas (3-7), a statistically significant decrease is evident. …”