Data_Sheet_1_Analysis of the global burden of cardiovascular diseases linked to exposure to ambient particulate matter pollution from 1990 to 2019.docx by Binbin Zou (11358315)

“…</p>Conclusion<p>The burden of CVDs linked to PM pollution has grown significantly from 1990 to 2019, with variations across regions and countries, highlighting the need for targeted prevention and pollution management strategies.…”

Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch... by Hongtao Zhang (167639)

“…</p>Results<p>SFAS significantly improved cardiac function in CHF rats. …”

Therapeutic efficacy of Clrn1 re-expression in Müller glia depends on expression level. by Hannah J. T. Nonarath (20861735)

“…(*p<0.05, **p<0.01, ***p<0.005, ****p<0.001; Two-way ANOVA; Significance shown compared to wild-type <i>gfap</i>:GFP without light stress). …”

Image 1_Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB pathway a... by Lei Li (29537)

“…The findings revealed that high-dose HXZQD significantly delayed the onset of EHS, reduced core body temperature elevations, and mitigated multi-organ injury, as evidenced by biochemical markers and histopathological examination. …”

Data Sheet 1_Huoxiang Zhengqi dropping pills alleviate exertional heat stroke–induced multiple organ injury through sustaining intestinal homeostasis via regulating MAPK/NF-κB path... by Lei Li (29537)

“…The findings revealed that high-dose HXZQD significantly delayed the onset of EHS, reduced core body temperature elevations, and mitigated multi-organ injury, as evidenced by biochemical markers and histopathological examination. …”

The T-type voltage-gated Ca²⁺ channel Ca_V3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin by Haixin Bi (6867632)

“…This was evidenced by a decreased expression of tight junctions (ZO-1, occludin) and adherens junctions (β-catenin, E-cadherin), as well as enhanced cytoskeletal rearrangement. …”

Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

The quality metrics of 4C-seq data. by Tingting Jiang (169999)

“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”

Table 1_From feed to field: effect of dietary protein level and use of a blend of feed additives on gaseous emissions from growing-finishing pig slurry.docx by Esperanza Fuertes (20628794)

“…NH₃ emissions from the room and slurry pit decreased by over 38%, while CH₄ emissions, although higher in LP diets, were mitigated with the LPA diet. …”

<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor by Mo-Fei Li (21624535)

“…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …”

Raw data for quantitative real-time PCR analysis. by Hyerim Park (303433)

“…Compared to mice on the P-MAL diet alone, Lp^WJL supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”

Generated spline library. by Zhe Hu (787283)

“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”

DataSheet1_Dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model.docx by Yuhan Zhang (2792089)

“…Retinal levels of inflammatory factors were significantly decreased in Ala-Gln-treated diabetic rats. …”

Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf by Qi Dong (119569)

“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”

Data Sheet 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx by Peijin Li (220400)

“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”

Supplementary file 3_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg by Yuhui Zhang (399617)

“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”

Supplementary file 2_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Table 1_Oxymatrine for inflammatory bowel disease in preclinical studies: a systematic review and meta-analysis.docx by Xuan Zhao (356028)

“…The data analysis results indicated that the disease activity index (DAI), histopathological score (HS), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), nuclear factor-κB (NF-κB), and myeloperoxidase (MPO) activity in the IBD animal models significantly decreased following intervention with oxymatrine. …”

Supplementary file 2_Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fi... by Shuting Li (6552)

“…In a murine model of peritoneal fibrosis induced by intraperitoneal injection of 4.25% PD fluid, SAL treatment significantly mitigated peritoneal fibrosis, as evidenced by reduced collagen deposition, decreased protein expression of α-smooth muscle actin and Collagen I, and a thinner peritoneum. …”

Image 6_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg by Ming Lei (161082)

“…The study of the supply of ecosystem services and the demand and consumption of ecosystem services by human society, and the analysis of the supply and demand characteristics and flow relationships of ecosystem service flows are of great significance for the management of regional ecosystems and the development of ecological compensation. …”