Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets by Karl Knipper (15016346)

“…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …”

H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment. by Aditya Parmar (22331873)

“…<b>(B)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within SEACR-defined consensus peak regions. The significance threshold was a false-discovery rate <0.05, as defined by DiffBind [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref065" target="_blank">65</a>] (n = 4). …”

Data Sheet 1_Strategies for enhancing yield and quality of forage-grain dual-purpose ratoon rice: role of first-season density and nitrogen management.docx by Yuyuan Ouyang (15350374)

“…Results showed that: Silage yield increased significantly with higher density and nitrogen input. …”

Table2_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

Table4_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

Table1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

DataSheet1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.pdf by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

Supplementary file 1_Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a sy... by Yajing Li (1394572)

“…Meta-analysis demonstrated that LSW plus conventional treatment significantly outperformed conventional treatment alone in shortening vesicle cessation time [MD = −1.44, 95% CI (−1.66, −0.93), p < 0.00001, I² = 70%], accelerating scab formation (MD = −1.72, 95% CI (−2.09, −1.35), p < 0.00001, I² = 38%), reducing scab shedding time (MD = −2.22, 95% CI (−3.64, −0.80), p = 0.002, I² = 36%), decreasing time to pain resolution (MD = −2.46, 95% CI (−3.52, −1.39), p < 0.00001, I² = 0%), and shortening pain persistence duration (MD = −1.97, 95% CI (−2.49, −1.46), p < 0.00001, I² = 86%). …”

Supplementary file 2_Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a sy... by Yajing Li (1394572)

“…Meta-analysis demonstrated that LSW plus conventional treatment significantly outperformed conventional treatment alone in shortening vesicle cessation time [MD = −1.44, 95% CI (−1.66, −0.93), p < 0.00001, I² = 70%], accelerating scab formation (MD = −1.72, 95% CI (−2.09, −1.35), p < 0.00001, I² = 38%), reducing scab shedding time (MD = −2.22, 95% CI (−3.64, −0.80), p = 0.002, I² = 36%), decreasing time to pain resolution (MD = −2.46, 95% CI (−3.52, −1.39), p < 0.00001, I² = 0%), and shortening pain persistence duration (MD = −1.97, 95% CI (−2.49, −1.46), p < 0.00001, I² = 86%). …”

Table5_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

Table3_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx by Runzhou Ma (19758996)

“…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10^-4, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10^-5, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…”

Data Sheet 1_Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a systematic... by Yajing Li (1394572)

“…Meta-analysis demonstrated that LSW plus conventional treatment significantly outperformed conventional treatment alone in shortening vesicle cessation time [MD = −1.44, 95% CI (−1.66, −0.93), p < 0.00001, I² = 70%], accelerating scab formation (MD = −1.72, 95% CI (−2.09, −1.35), p < 0.00001, I² = 38%), reducing scab shedding time (MD = −2.22, 95% CI (−3.64, −0.80), p = 0.002, I² = 36%), decreasing time to pain resolution (MD = −2.46, 95% CI (−3.52, −1.39), p < 0.00001, I² = 0%), and shortening pain persistence duration (MD = −1.97, 95% CI (−2.49, −1.46), p < 0.00001, I² = 86%). …”

Data Sheet 1_Mitigating ammonium and nitrate leaching in rice-wheat crop rotation: efficacy of neem coated urea and compost co-application.pdf by Sandeep Kumar (145759)

“…Application of 125%-N significantly increased the total mineral N leaching. …”

Figure 6 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia by Sydney A. Skupa (18597728)

“…Asterisks denote the significance between antibiotic-receiving or water-receiving mice over time (*, <i>P</i> < 0.05). …”

Image 6_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

This is raw data of IL-1β ELISA. by Farzad Nasri (8941850)

“…IFN-β in contrast to Vit D decreased <i><i>Gal-9</i></i> gene expression. <i>β-<i>catenin</i></i> gene expression increased after IFN-β or Vit D treatment. …”

Different controller performance indicators 1. by Wanjun Zhang (496858)

“…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …”

Image 1_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Data Sheet 2_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Presentation 1_Efficacy of disitamab vedotin in non-small cell lung cancer with HER2 alterations: a multicenter, retrospective real-world study.pdf by Meiling Zhang (352540)

“…The most common adverse events included hand-foot syndrome (54.5%), asthenia (50.0%), decreased white blood cell count (45.5%), and liver impairment (45.5%). …”