Supplementary Material for: Non-Prescribed Use of Opioid Agonist Medications and Associations with Non-Fatal Overdoses: A Repeated Cross-Sectional Study Across a Decade of Reduced... by figshare admin karger (2628495)

“…Multinomial regression analyses showed no significant association between non-prescribed OAT use and increased risk of non-fatal overdoses. …”

Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”

Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... by Ying-han Deng (21604157)

“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”

Neurofilament light chain as a biomarker for hereditary ATTR amyloidosis − correlation between neurofilament light chain and nerve conduction study by Masateru Tajiri (19818114)

“…NfL levels significantly decreased with patisiran, although no significant changes were observed in CMAP and SNAP.…”

Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls by Linjie Peng (12553717)

“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”

Enamel matrix derivative in the treatment of tooth replantation: from a biological basis to clinical application by Yao Lin (1622536)

“…Although the pooled outcomes suggested increased incidence of surface resorption (RR=1.19, <i>P</i>=0.730) and decreased risk of inflammation resorption (RR=0.68, <i>P</i>=0.560) among replanted teeth with resorption in the EMD-treated group, neither difference was statistically significant.…”

Table 1_Short-term influence of Immufen™ on mild allergic rhinitis: a randomized, double-blind, placebo-controlled study.docx by Mamatha K (19843110)

“…</p>Results<p>CQAB supplementation demonstrated a significant (P < 0.05) improvement in Total Nasal Symptom Score (TNSS) compared to placebo and CGM. …”

Table 4_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Supplementary Material for: Phosphorus restriction prevents rapamycin-induced kidney damage in rats by Raya A.I. (19823163)

“…Results: When compared with placebo, rapamycin administration to Nx rats resulted in significant increases in IN (4.17±0.74 vs 1.51±0.53 %) and TD (14.45±1.51 vs 8.61±1.83 %). …”

DataSheet1_Vitamin D Deficiency and Associated Factors in Children: A Multicenter Study of 21,811 Samples in Southern China.docx by Chuican Huang (15107903)

“…</p>Results<p>Serum 25(OH)D levels decreased with age (p trend <0.001). VDD prevalence increased significantly from 3.7% (95% CI: 3.2, 4.3) in children aged 0–3 years to 43.5% (95% CI: 42.1, 45.0) in those aged 13–18 years. …”

Data Sheet 1_An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance.docx by Chenchen Zhang (324804)

“…</p>Conclusion<p>Increased P. vulgatus and B. fragilis, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.…”

Location map of the study area. by Chao Ma (207385)

“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”

Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i> by Shengan Zhu (19817727)

“…Expression analysis revealed significant upregulation of BbNoxs during fungal growth and infection. …”

Image 2_Exploring the antibacterial and anti-biofilm properties of Diacerein against methicillin-resistant Staphylococcus aureus.tif by Yingying Sun (568696)

“…Background<p>Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant clinical challenge due to its multidrug resistance. …”

Table 1_Association between oral health status and frailty in older adults: a systematic review and meta-analysis.docx by Jingwen Huang (232382)

“…Investigating the relationship between oral health and frailty in older adults is of significant importance for preventing frailty, ensuring the quality of life for older adults, and promoting healthy longevity.…”

Personality traits in people with multiple sclerosis: A systematic review and meta-analysis by Omid Mirmosayyeb (12431770)

“…Additionally, higher Neuroticism was significantly linked to increased anxiety (<i>r</i> = 0.78), depression (<i>r</i> = 0.53), and fatigue (<i>r</i> = 0.35), and Conscientiousness was significantly correlated with decreased Expanded Disability Status Scale (EDSS) (<i>r</i> = −0.21) and Symbol Digit Modalities Test (SDMT) (<i>r</i> = 0.13). …”

Different model detection results comparison. by Chunhua Yang (346871)

“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”