Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx حسب Xiaozhen Huang (5858690)

"…Background<p>Isolated growth hormone deficiency type II (IGHD II) is an autosomal dominant disorder characterized by a GH1 gene variant resulting in a significant reduction in growth hormone (GH) secretion and a subsequent decrease of plasma insulin-like growth factor 1 (IGF-1) levels and eventual growth impairment.…"

Table3_Causal relationship between antihypertensive drugs and Hashimoto’s thyroiditis: a drug-target Mendelian randomization study.xlsx حسب Bing Cui (179696)

"…Moreover, genetically mimicking the use of loop diuretics (OR [95% CI]: 0.94 [0.91, 0.97]; p = 3.57×10^-5) and thiazide diuretics (0.98 [0.96, 0.99]; p = 3.83×10^-3) showed a significant association with a decreased risk of HT only in European population. …"

Table 1_Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observat... حسب Yuya Koide (22261300)

"…</p>Results<p>GLP-1RA therapy significantly reduced HbA1c, body weight, and body fat percentage at 12 months. …"

Experiments (Crystal violet assay). حسب Takanori Kitagawa (20727226)

"…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …"

Image 5_Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.tiff حسب Mireille Ngokingha Tchouto (20812811)

"…</p>Results<p>While the B cell proportion in young and non-immune experienced animals did not significantly change from 2 to 5 days post osteotomy in the hematoma, we found a significant decrease of the B cell proportion in the immune experienced mice, which was accompanied by the decreased expression of B cell specific genes, suggesting a specific response in immune experienced animals. …"

Cascade Nanozyme-Loaded Sprayable Hydrogels for Fibroblast Rejuvenation and Diabetic Wound Regeneration حسب Xinyi Zhang (36040)

"…Multifunctional composite wound dressings hold significant promise for diabetic wound healing. However, the detrimental role of the advanced glycation end-products (AGEs)-reactive oxygen species (ROS) cycle in impeding wound repair remains underexplored. …"

Table1_Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pat... حسب Boris Jakopovic (9265517)

"…Even with treatment advancements, the survival rates for these patients remain suboptimal. There is a significant focus on developing multi-targeted therapies due to the common issue of drug resistance in standard and targeted cancer treatments. …"

Scenario 1. Moderate patient with STAT-ON™. حسب Daniel Rodriguez-Martin (22411006)

"…<div><p>Parkinson’s Disease (PD) is a progressive neurodegenerative disorder affecting millions of patients worldwide, with significant economic and social implications. The increasing prevalence of PD, coupled with rising healthcare costs, necessitates cost-effective solutions for patient management. …"

Table 4_Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021.doc حسب Shujun Tan (20011518)

"…</p>Results<p>The global burden of NE has significantly declined over the past three decades. Between 1990 and 2021, the global ASIR decreased from 20.22 to 17.16, while the number of cases fell from 1,295,891.1 to 1,061,448.15, reflecting an 18.09% reduction. …"

Electrophysiological characterization of <i>C. elegans</i> body-wall muscles. حسب Xuexing Du (20624042)

"…The top section of each column illustrates the currents in different mutants, while the bottom section depicts the ionic currents obtained by subtracting the corresponding mutant currents from the total wild type (WT) currents, highlighting a significant decrease in <i>shk-1(lf)</i> and a slight reduction in <i>slo-2(lf)</i> mutants. …"

ESR Data for حسب Takanori Kitagawa (20727226)

"…YCW-H demonstrated significant anti-proliferative effects on MCF7 cells, reducing cell growth by 58.7% ± 6.9 even when physically separated from the cells by a plastic wall. …"

Presentation 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf حسب Liang Sui (20912441)

"…DALYs and years of life lost (YLLs) rates generally decreased, with intervals of stabilization and minor increases, while years lived with disability (YLDs) showed significant fluctuations. …"

Scenario 2. Advanced patient with STAT-ON™. حسب Daniel Rodriguez-Martin (22411006)

"…<div><p>Parkinson’s Disease (PD) is a progressive neurodegenerative disorder affecting millions of patients worldwide, with significant economic and social implications. The increasing prevalence of PD, coupled with rising healthcare costs, necessitates cost-effective solutions for patient management. …"

Image_3_Effects of tree species identity on soil microbial communities in Juglans nigra and Quercus rubra plantations.TIFF حسب Juan P. Frene (12227753)

"…Conversely, Q. rubra tends to decrease these indices. Significant disparities in microbial composition between the two tree species were evident, with J. nigra exhibiting enrichment in certain taxa such as Nitrospira, Geobacter, and Bacillus while Q. rubra showed enrichment in others like Acidobacteriota and ectomycorrhizal fungi. …"

Data Sheet 1_Characterization of vaginal microbiota across female reproductive phases.zip حسب Qingzhi Zhai (21265412)

"…</p>Results<p>Microbial communities show significant variations across the different reproductive phases. …"

Image 1_Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials... حسب Virginie Piffaut (22399978)

"…</p>Results<p>While ascorbic acid did not exhibit any efficacy versus its vehicle in limiting skin hyperpigmentation induced by HEV, the use of 2-MNG (0.5 or 1%) led to an early significant decrease in HEV-induced pigmentation, which was sustained until the end of the study, as evidenced by colorimetry and significantly scored by visual assessment. …"

Data Sheet 1_Effect of zinc oxide nanoparticle supplementation on parasite infection and rumen environment of grazing lambs.pdf حسب Matej Leško (20867141)

"…The number of eggs per gram of feces was quantified on days D14, D20, D28, D42, D56, D70, D84, D98, and D107 post-infection. There was a significant decrease in egg shedding from D42 onwards in the ZINC group, and from D56 and D70 onwards in the CONTROL group. …"

Table 1_Causal insights into the school-family-research integrated health promotion program for overweight and obesity: the independent role of moderate-to-vigorous physical activi... حسب Xuehui Zhang (1920034)

"…</p>Results<p>While both groups showed a time effect (p < 0.001), the intervention resulted in a significant decrease in body fat percentage (BFP) compared to the control group (p < 0.001, p < 0.038). …"

Table 3_The inhibitory effects of 7ND protein on osteoclast differentiation in apical periodontitis.xlsx حسب Zhang-Zhang Ji (21611168)

"…In AP rats treated with 7ND protein, X-ray imaging and micro-computed tomography demonstrated a significant decrease in lesion volume and area in the periapical regions compared to AP rats treated with PBS.…"

Table 2_Pronounced impairment of B cell differentiation during bone regeneration in adult immune experienced mice.xlsx حسب Mireille Ngokingha Tchouto (20812811)

"…</p>Results<p>While the B cell proportion in young and non-immune experienced animals did not significantly change from 2 to 5 days post osteotomy in the hematoma, we found a significant decrease of the B cell proportion in the immune experienced mice, which was accompanied by the decreased expression of B cell specific genes, suggesting a specific response in immune experienced animals. …"