Search alternatives:
significant source » significant burden (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
significant source » significant burden (Expand Search)
greatest decrease » treatment decreased (Expand Search), greater increase (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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Global, regional and national burden of colorectal cancer and its risk factors, 1990-2021: a systematic analysis for the GBD 2021
Published 2025“…<p dir="ltr"><b>Importance: </b>Colorectal cancer (CRC) constitutes a significant segment of the global cancer burden, thereby warranting an in-depth epidemiological appraisal to inform strategic public health interventions and resource allocation. …”
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Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture
Published 2025“…Positive selection of the TMAO-producing enzyme gene <i>fmo3</i> in supergiant amphipods (Liu et al. 2022) and in the Mariana Snailfish (with more putative promoters compared to <i>fmo3</i> in shallower teleosts; Wang et al. 2019), plus and increased number of <i>fmo3</i> genes in the Yap Trench snailfish (Mu et al. 2021), add strong support to the TMAO-piezolyte hypothesis. For teleosts, we have hypothesized that the need for TMAO may prevent fishes from living at the greatest depths (Jamieson and Yancey 2012). …”