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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
high decrease » slight decrease (Expand Search), high disease (Expand Search), weight decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
high decrease » slight decrease (Expand Search), high disease (Expand Search), weight decreased (Expand Search)
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20301
Table 3_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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20302
Data Sheet 1_Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.pdf
Published 2025“…Introduction<p>Lung cancer is characterized by a poor prognosis and is a significant comorbidity of chronic obstructive pulmonary disease (COPD). …”
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20303
Table1_Leaf functional traits highlight phenotypic variation of two tree species in the urban environment.xlsx
Published 2024“…Norway Maple gas exchange values decreased as the growing season progressed, as expected by ontogeny. …”
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20304
Table8_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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20305
Data Sheet 1_Comparative evaluation of artificial saliva and complete artificial saliva as solvent vehicles for in vitro toxicity testing of oral tobacco products.docx
Published 2025“…</p>Results<p>The results showed comparable nicotine extraction efficiency between AS and CAS, with no significant impact from pouch cutting size or extraction duration. …”
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20306
Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf
Published 2025“…Subsequently, the patient underwent whole-brain radiotherapy. Significant improvements were noted in her headache and insomnia symptoms. …”
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20307
Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
Published 2025“…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …”
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20308
Supplementary file 1_Differential adaptations of japonica rice to submergence stress during the tillering stage under various seedling cultivation and transplanting methods.docx
Published 2025“…Over two-thirds of tillers survived under complete submergence for up to 7 days during the tillering stage. Submergence significantly affected POD and SOD activities, MDA and PRO contents, and SPAD values, characterized by initial increases followed by decreases in antioxidant enzyme activities, MDA accumulation, and PRO content elevation. …”
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20309
Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx
Published 2025“…In contrast, CAVI showed no significant correlation with blood pressure or body weight. …”
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20310
Data Sheet 1_Impact of artificial intelligence on electronic health record-related burnouts among healthcare professionals: systematic review.pdf
Published 2025“…Nevertheless, EHR-related workload has been considered as a significant contributor to healthcare professionals’ burnout, a syndrome associated with emotional exhaustion, depersonalization, and reduced personal accomplishment. …”
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20311
Image 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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20312
CLAD_sequence_files
Published 2025“…Association with CLAD severity was driven by changes in phosphoethanolamine and phosphocholine lipids that increased and decreased, respectively, and metabolites from the bacterial pathogen <i>Pseudomonas aeruginosa</i>. …”
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20313
Table 1_Association between androgenetic alopecia and psychological well-being: a systematic review and meta-analysis.docx
Published 2025“…However, no significant difference was observed in general distress (pooled SMD = -0.01, 95% CI [-0.39,0.37], p = 0.97). …”
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20314
Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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20315
LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p
Published 2025“…<p>Cerebral ischemia-reperfusion (CI/R) injury is a significant hurdle in ischemic stroke treatment. Substantial evidence indicates that long non-coding RNAs (lncRNAs) are implicated in CI/R injury. …”
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20316
Data Sheet 2_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip
Published 2025“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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20317
DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx
Published 2024“…Although the population of F4/80<sup>+</sup>CD11b<sup>+</sup> intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1<sup>+</sup>MerTK<sup>+</sup>) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”
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20318
Data Sheet 1_Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss.pdf
Published 2025“…We also observed decreased percentages of IFN-γ<sup>+</sup> pNK cells (49% vs 25.2%, p=0.027) after exercise.…”
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20319
Image 4_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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20320
Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf
Published 2025“…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …”