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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
high decrease » slight decrease (Expand Search), high degree (Expand Search), high disease (Expand Search)
increase » increased (Expand Search)
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19381
Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx
Published 2025“…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”
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19382
Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx
Published 2025“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”
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19383
Table 1_The effect of khat chewing on sexual desire among adults in North East Ethiopia: a propensity score-match analysis.docx
Published 2025“…Background<p>Although the number of khat chewers has increased from time to time in Ethiopia, the direction (increased or decreased) of khat chewing on sexual desire is not well known due to the absence of adequate studies. …”
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19384
Table 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx
Published 2025“…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …”
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19385
Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx
Published 2025“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”
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19386
Table 2_Survival assessment in extremely preterm neonates in a middle-income setting.docx
Published 2025“…Notably, survival after extremely preterm birth was associated with significant morbidity.</p>…”
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19387
Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX
Published 2024“…</p>Conclusion<p>Our study explored a significant correlation between PHDI and biological aging, indicating that adherence to PHD may prevent biological aging.…”
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19388
Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff
Published 2024“…Introduction<p>Diabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions. …”
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19389
Data - <i>trus</i>RNAi wing size measurement.
Published 2025“…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
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19390
Image5_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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19391
Characteristics of children in the study.
Published 2025“…</p><p>Conclusions:</p><p>This study found a significant association between myopia and worse HRQOL in primary and secondary school children. …”
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19392
Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx
Published 2025“…Among 15 lupus nephritis patients, 86.7% achieved complete renal response. Significant hematologic improvement was observed in autoimmune hemolytic anemia and thrombocytopenia. …”
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19393
Table_1_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,...
Published 2024“…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …”
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19394
Image6_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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19395
ORS and zinc coverage, by country, DHS data only.
Published 2025“…Our findings demonstrate the long-term success of the SUZY project and provide insights into best practices for impactful zinc scale-up programs including significant pre-launch implementation research addressing key knowledge gaps and partnering with research organizations. …”
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19396
Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf
Published 2024“…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”
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19397
Image 3_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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19398
Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i>
Published 2025“…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …”
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19399
Image_1_Effect of probiotic supplementation combined with bismuth-containing quadruple therapy on gut microbiota during Helicobacter pylori eradication: a randomized, double-blind,...
Published 2024“…After treatment, the GSRS score decreased significantly in the probiotic group (p = 0.039). …”
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19400
Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf
Published 2025“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”