Data Sheet 2_Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells.docx by Joshua Flynn (2544523)

“…</p>Methods<p>This study utilised a targeted single-cell multi-omics approach to characterise peripheral blood mononuclear cell (PBMC) populations and their transcriptomic profiles in an Irish cohort of people with (i) sepsis and (ii) bacteraemia without sepsis (defined as clinically significant positive blood culture without sepsis as assessed by the Clinical Microbiology service).…”

Supplementary file 2_Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fi... by Shuting Li (6552)

“…By intersecting 148 drug targets with the 249 disease targets, four therapeutic targets for SAL treatment against peritoneal fibrosis were pinpointed: cathepsin S, VDR, plasminogen activator urokinase, and galectin 3. In a murine model of peritoneal fibrosis induced by intraperitoneal injection of 4.25% PD fluid, SAL treatment significantly mitigated peritoneal fibrosis, as evidenced by reduced collagen deposition, decreased protein expression of α-smooth muscle actin and Collagen I, and a thinner peritoneum. …”

Image 2_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

“…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”

Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma by Zelei Yang (18491142)

“…For comparisons indicated by brackets over the treatment groups being compared, * = <i>P</i> < 0.05 and NS = not significant by an ordinary one-way ANOVA with Šídák’s multiple comparisons test. …”

Changes in functional connectivity between NREM and REM – comparison of in vivo experimental and in silico modeling data. by Michael Satchell (21560808)

“…However, animals that underwent CFC exhibited a significant increase in the number of cell pairs that strengthen functional connectivity (during REM), as compared to baseline (K-S test comparing baseline and CFC <i>p</i> = 6.0102e-126). …”

Supplementary Material for: Analysis of Brain Functional Connectivity in Patients with Delayed Encephalopathy After Carbon Monoxide Poisoning Based on Functional Near-Infrared Spec... by figshare admin karger (2628495)

“…Compared with the control group, the brain network of DEACMP patients showed heterogeneity from left PC to right PC; Left PC~Left PMC; Left PC~right PMC; Left PC~Left DLPFC ,etc.The functional connectivity strength between the left PC and the right DLPFC area has significantly decreased. All these differences were statistically significant (P<0.05, FDR adjusted). …”

The 16S rRNA sequencing raw data for the study titled Effects of high-dose glucocorticoids on gut microbiota in the treatment of Graves' ophthalmopathy by Xinhuan Su (21147710)

“…The short chain fatty acids (SCFAs)-producing ability in GO patients’ gut after high-dose GCs administration was significantly decreased. The 5-hydroxytryptamine (5-HT) levels significantly increased in gut of GO patients after administering high-dose GCs. …”

Bee bread shows therapeutic and protective effects by alleviating inflammation, oxidative stress, and apoptosis on acetic acid-induced gastric ulcer in rats by Hatice Colak (20773009)

“…In BB-pretreated ulcer group, MPO-(saline\BB, 39.9±3.7 U/g;22.2±2.2 U/g), caspase-3 (0.40±0.07 ng/g;0.18±0.01 ng/g) and IFN-γ (15.46±1.76;9.51±1.95 ng/g) levels decreased and TNF-α (31.77±5.13;18.94±2.59 ng/g) reduced only in BB-treated ulcer group. …”

Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway by figshare admin karger (2628495)

“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”

Image 4_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. …”

Image 5_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. …”

Table 2_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. …”

Image 3_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. …”

Image 2_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. …”

Table 5_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 4_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 6_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 3_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

Table 2_Effects of dietary NDF/NFC ratios on in vitro rumen fermentation, methane emission, and microbial community composition.docx by Jichao Li (1973251)

“…The degradation rates of dry matter (DM), neutral detergent fiber (NDF), and acid detergent fiber (ADF) decreased, showing a quadratic response (p = 0.018). …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…IOP decreased 6 hours post-injection and by day 1 had returned to near baseline levels. …”