Supplementary file 1_Tacrolimus exposure during the three-month period following allogeneic stem cell transplantation predicts overall survival.docx by Alzbeta Zavrelova (4885270)

“…Tacrolimus volume of distribution was 127.1 L and was not affected by any of the tested covariates, whereas clearance decreased with age according to the equation CL=7.94×e−0.0085×age and was reduced by 23% in patients who underwent repeat transplantation.…”

Image 1_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Table 1_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Image 1_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.tif by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Table 1_An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021.xlsx by Zhuowen Hu (20431616)

“…High Body Mass Index (BMI) is a significant risk factor, contributing substantially to GBTC mortality and Disability-Adjusted Life Years (DALYs). …”

Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx by Jae-Sung Lim (532986)

“…Patients suspected of pre-stroke cognitive decline were excluded. Decliners [defined by a decrease of ≥3 Mini-Mental State Examination (MMSE) points annually or an absolute drop of ≥5 points between evaluations, confirmed with detailed neuropsychological tests] were compared with age- and stroke severity-matched non-decliners. …”

Table 1_Multiparametric MRI assessment of renal blood oxygenation, fat content, and hemodynamics in an animal model of metabolic dysfunction-associated steatotic liver disease.docx by Chao Wang (146527)

“…Compared with those at week 14, renal T2* significantly decreased at week 20, FF increased at week 20, and serum creatine levels increased at week 24. …”

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx by Gerui Li (15648920)

“…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …”

Data Sheet 1_Valve-in-valve transcatheter aortic valve replacement (TAVR) leads to lower device success compared to TAVR in native stenosis.pdf by Michael Paukovitsch (16428786)

“…While ViV-TAVR decreased peak and mean gradients significantly, in 31% of patients elevated mean gradients (≥20 mmHg) were observed at discharge. …”

POm shows pronounced response disparity to active and passive whisker stimuli. by Anton Sumser (21021061)

“…Rate increase: 4/11 neurons, rate decrease: 1/11 neurons (light gray), non-significant: 6/11 neurons. …”

Table 1_Deletion of the GntR8 transcriptional regulator impairs Brucella abortus intracellular survival and virulence by modulating stress response genes.xlsx by Shuwen Li (5058398)

“…The results demonstrate that deletion of gntR8 markedly impairs intracellular survival of B. abortus in RAW264.7 cells and significantly reduces virulence in a mouse infection model. …”

Supplementary Material for: Long-term outcomes and clinical factors associated with conventional therapy failure in intestinal Behçet’s disease: A retrospective cohort study in Jap... by figshare admin karger (2628495)

“…Concomitant glucocorticoid use significantly decreased from 12.7±11.7 mg/day at baseline to 2.4±2.5 mg/day at 1 year (p<0.001). …”

Figure 1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action by James P.B. O’Connor (15037863)

“…<p>Determining drug mechanism of action in Calu6 cells <i>in vitro</i>. <b>A,</b> Increased retention of the fluorescent cytotoxic metabolite of banoxantrone, AQ4, as oxygen concentration decreased, with (<b>B</b>) example images shown for cells exposed to 10 µmol/L of banoxantrone differing oxygenation conditions. …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…The regulatory mechanism of MrgC on UPR^mt was further explored in N2a and 293T cells.</p>Results<p>Mice with bone cancer pain showed improved mRNA and protein levels of UPR^mt-related molecules, increased MMP and ATP, decreased mitochondrial ROS levels in the spinal cord after receiving an intrathecal injection of BAM8-22. …”

Table1_Drought stress reduces arbuscular mycorrhizal colonization of Poncirus trifoliata (L.) roots and plant growth promotion via lipid metabolism.docx by Wei Zhang (405)

“…Results indicated that AM fungal inoculation significantly promoted the drought tolerance of P. trifoliata (L.), with the effect size decreasing along with drought severity. …”

Table 2_Cost-effectiveness of the 3E model in diabetes management: a machine learning approach to assess long-term economic impact.docx by Supriya Raghav (21412907)

“…</p>Methods<p>We conducted an observational longitudinal descriptive analysis involving 320 patients, who were grouped into intervention and control groups over a 24-month period.</p>Results<p>The 3E model demonstrated significant cost reductions, with the intervention group achieving a 74.3% decrease in total costs compared to 41.8% in the control group while maintaining the same level of glycemic control. …”

Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx by You Yu (2102071)

“…Furthermore, the decreased levels of IPA in brain contributed to the attenuated aryl hydrocarbon receptor (AhR) signaling characterized by increased expression of downstream elements, including glutamate transporters and GABA receptors. …”

Supplementary file 1_Comprehensive real-time metabolic profiling of peripheral blood mononuclear cells reveals important methodological considerations for immunometabolism research... by Michael Macleod (22516823)

“…Extended blood processing time significantly lowered T cell activation capacity in PBMCs, evidenced by decreased responses of mitochondrial and glycolytic ATP supply to CD3/CD28 activation.…”

Data Sheet 1_Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus).pdf by Bingbu Li (21097373)

“…Lysozyme enzyme activity increased, whereas catalase and alkaline phosphatase enzyme activities decreased. …”

Table 1_Optimization of Artemisia ordosica crude polysaccharides on milk fatty acid composition in lactating donkeys and their effects on rectal microbiome and lactation performanc... by Fanzhu Meng (20418071)

“…AOCP elevated acetate and butyrate in the rectum and the activity of enzymes related to lipid metabolism such as stearoyl-CoA desaturase, and increased the relative abundance of beneficial bacteria (Eubacterium hallii group, Prevotella, Ruminococcus), while decreasing potentially pathogenic bacteria Streptococcus and norank_f_Lachnospiraceae. …”